关键词: 流行性乙型脑炎减毒活疫苗, 强化免疫, 接种率, 发病率

Abstract:

Objective　To determine the effectiveness of Japanese encephalitis (JE) mass immunization campaign in Guizhou in 2008, providing evidence for the development of control strategies. Methods　Comprehensive analysis was performed based on the reports and investigation results during mass immunization campaign and epidemic information from the National Diseases Reporting System before and after the launch. Results　A total of 1 503 052 children were immunized, the reported immunization coverage being 96.72%, the estimated coverage based on the population data 91.82%. The provincial incidence of JE was 0.85/100 000 in 2008, a decrease of 44.08% compared to that in 2007. Sharp decline in the incidence among target population was observed in various areas and counties to a more significant extent than that in non-target population. The incidence also decreased in each age group in 2008, yet the 8?month to 6-year-old group still had the highest incidence. Above average level of incidence was seen in Anshun, Qianxinan, Tongren and Bijie, and an increase of 111.59% was present in Anshun when compared to that in 2007. The incidence rates of 7 to 10-year-old group in Anshun, Qianxinan were both above the provincial average level, which increased by 117.83% and 66.32% when compared to those in 2007. Conclusion　The expected goal of the JE mass immunization campaign had been attained. Younger children, especially those aged 8 months to 6 years in the province, were still the key group for prevention and control of this disease. Importance should be attached to the prevention and control of JE in such key areas as Anshun and Qianxinan.

Key words: Japanese encephalitis attenuated live vaccine, Catch-up vaccination, Inoculation rate, Incidence rate