中国媒介生物学及控制杂志

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莱姆病关节炎的循证治疗

陈建1;耿震2;侯学霞2;万康林2   

  1. 1新乡医学院预防医学教研室 新乡453003;2中国疾病预防控制中心传染病预防控制所
  • 出版日期:2006-04-20 发布日期:2006-04-20

The Evidence-based Treatment for Arthritis of Lyme Disease

CHEN Jian; GENG Zhen; HOU Xue-xia; WAN Kang-lin   

  1. Department of Preventive Medicine, Xinxiang Medical College, Xinxiang 453003, China
  • Online:2006-04-20 Published:2006-04-20

摘要: 目的 通过对现有医学证据的检索和评价,指导莱姆病关节炎的治疗。方法 首先提出临床问题,然后对Cochranelibrary(2005.2)、Medline(1966~2005.5)、中国生物医学文献(光盘)数据库(CBMDISC,1978~2005)和中文科技期刊全文数据库(VIP,1989~2005)等网站进行检索,并对检索结果进行评价,检索词包括“Lyme disease,arthritis”和“Systematical review or randomized control trial or case control trial”。结果 通过检索,共获得11篇相关文献,其中3篇随机对照试验,3篇病例对照试验和5篇病例报道。资料显示大剂量的青霉素等抗生素用于莱姆病关节炎有较好的治疗效果。该治疗方法适用于我们研究的病例。结论 通过证据的检索和评价,对该患者采用大剂量的青霉素治疗,获得了满意效果。

关键词: 莱姆病, 关节炎, 循证治疗

Abstract: Objective We searched and reviewed medical evidence to find treatment for arthritis of Lyme disease. Methods Firstly,we put forward the clinical questions. secondly,we searched medical evidence from Cochrane library(2005.2),Medline(1966-2005.5),CBMDISC(1978-2005) and VIP(1989-2005),and then we reviewed the searching results. The kords we used were “Lyme disease; arthritis” and “Systematical review or randomized control trial or case control trial”. Results By our searching; we got 11 papers including 3 randomized control trial; 3 case control trial and 5 other case reports. It showed that large dose penicillin had a good effect on arthritis of Lyme disease. The results can be used to treat our patient. Conclusion After treating the patient based on those evidence; we cured the patient with large dose penicillin and got a satisfied effect.