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鼠传疾病相关疫苗研究进展

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  • 1. 中国人民解放军 63750部队医院疾病预防控制科, 陕西西安 710043;
    2. 中国人民解放军 63750部队医院, 陕西 西安 710043
冯群岭,男,硕士,副主任医师,主要从事传染病防控研究,E-mail:397068818@qq.com

收稿日期: 2022-05-19

  网络出版日期: 2022-10-14

基金资助

军队后勤科研项目(CZZ19J017,145AHQ080005005X)

Advances in research on vaccines for rodent-borne diseases

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  • 1. Department of Disease Control and Prevention, PLA 63750 Military Hospital, Xi'an, Shaanxi 710043, China;
    2. PLA 63750 Military Hospital, Xi'an, Shaanxi 710043, China

Received date: 2022-05-19

  Online published: 2022-10-14

Supported by

Military Logistics Scientific Research Project (No.CZZ19J017,145AHQ080005005X)

摘要

鼠传疾病大多是人兽共患的自然疫源性疾病。啮齿动物因种类多、分布广、繁殖能力强而危害严重,随着城市化进程加快、啮齿动物栖息地破坏、人类与啮齿动物接触可能性增加等,多种鼠传疾病的流行区域不断扩大,对鼠传疾病的防治带来严峻的考验和挑战。疫苗接种是最有效的预防和控制疾病的手段,相关疫苗的研发生产大大缓解了国家医疗卫生系统的压力。当前鼠传疾病相关疫苗包括传统疫苗(灭活疫苗、减毒活疫苗)和新型疫苗(基因工程疫苗)。该文系统概述了鼠传疾病疫苗研发的主要进展和未来展望。

本文引用格式

冯群岭, 刘敏, 白英, 黄亚楠, 李颜, 王丹, 史文龙, 王思奇, 司海瑞, 王红红 . 鼠传疾病相关疫苗研究进展[J]. 中国媒介生物学及控制杂志, 2022 , 33(5) : 760 -764 . DOI: 10.11853/j.issn.1003.8280.2022.05.027

Abstract

Most rodent-borne diseases are naturally occurring zoonotic infections.Rodents pose a serious threat due to their diverse species,wide distribution,and strong reproductive ability.With accelerating urbanization,expanding rodent habitat destruction,and increasing human-rodent contact,the epidemic areas of many rodent-borne diseases are enlarging,which poses greatly challenges to the prevention and control of rodent-borne diseases.Vaccination is the most effective means of disease prevention and control.The development and production of vaccines has greatly eased the pressure on the national health care system.Current vaccines for rodent-borne diseases include traditional (inactivated and live attenuated vaccines) and new (genetically engineered vaccines) types.This paper systematically summarized the progress and future prospects of vaccine development for rodent-borne diseases.

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