中国媒介生物学及控制杂志 ›› 2009, Vol. 20 ›› Issue (6): 569-572.

• 论著 • 上一篇    下一篇

云南省嗜人按蚊传播区疟疾防治对策研究

李华宪, 陈国伟   

  1. 云南省寄生虫病防治所、云南省疟疾研究中心(思茅 665000)
  • 收稿日期:2009-06-20 出版日期:2009-12-20 发布日期:2009-12-20
  • 作者简介:李华宪(1956-),女,副主任医师,应急办公室主任,主要从事疟疾防治研究、寄生虫及虫媒病毒性疾病疫情及应急管理工作。
  • 基金资助:

    世界卫生组织(WHO)/卫生部项目(CH/MAL/.001)

Study on malaria control strategies in the malaria epidemic areas transmitted by Anopheles anthropophagus in Yunnan province

 LI Hua-Xian,  CHEN Guo-Wei   

  1. Yunnan Institute of Parasitic Diseases, Simao 665000, Yunnan Province, China
  • Received:2009-06-20 Online:2009-12-20 Published:2009-12-20

摘要:

【摘要】 目的 为云南省嗜人按蚊分布区疟疾控制和消除提供科学、经济、有效的防治对策及监测方法。方法 按照“嗜人按蚊分布区疟疾综合防治对策研究项目实施计划”规定的方法开展研究。结果 (1) 嗜人按蚊分布于云南省35个县(市),是滇东北地区8个县(市)的主要传疟媒介。(2) 筛选出不同疟疾发病率层次的疟疾防治对策分别是:发病率在10/万以上的乡(镇)用DDT(或其他替代杀虫剂)室内滞留喷洒及溴氰菊酯处理蚊帐,氯伯8日疗法治疗现症患者,单一伯喹8日疗法休根,氯伯2日疗法对发热患者进行假定性治疗及在疟疾暴发流行时用氯、伯4日疗法进行预防性全民治疗。发病率1/万~10/万的乡(镇)用氯喹1200 mg+伯喹180 mg治疗患者及溴氰菊酯处理全村居民蚊帐。发病率在1/万以下的乡(镇)仅用氯喹1200 mg,伯喹180 mg治疗患者。(3) 各县在2002-2006年的现场应用中,根据以上防治对策采取分层防治的策略,均取得使发病率大幅度下降的防治效果。结论 通过调查摸清了嗜人按蚊在云南省的分布范围、分布特征及规律,为该区域媒介防治措施的制定提供了科学依据。所提出的发病率在1/万以下、1/万~10/万、10/万以上地区防治对策的特点是经济、简便、高效、环保,为当地大面积低疟区疟疾防治解决了一个关键的技术难题,在后续5年的现场防治中已经产生较好的经济和社会效益。

关键词: 嗜人按蚊, 疟疾, 防治对策, 现场应用

Abstract:

【Abstract】 Objective Provide scientific, economic and effective control strategies and surveillance methods for malaria control and elimination in the epidemic areas transmitted mainly by Anopheles anthropophagus as main vector in Yunnan province. Methods The study  was  carried  out  according  to  the  methods  formulated  by  the execution  plan  of  malaria  integrated  control  strategies in An.anthropophagus distribution areas.  Results An. anthropophagus distributed in 35 counties in Yunnan province, which was the main malaria vector at 8 counties of northeast Yunnan.  Different malaria control strategies were selected according to malaria incidences. Indoor residue spraying of DDT (or other insecticides) and nets treated by deltamethrin were used in the areas where malaria incidence was higher than 10 per ten thousand population. Eight days radical treatment (chloroquine 1200 mg+primaquine 180 mg) was used to cure patient. These patients who had malaria attack history during malaria season of the year would been given primaquine 180 mg (taken it divided into 8 days) for the elimination of malaria in the period of malaria cease transmission season. Chloroquine 600 mg (taken by 1 day) and primaquine 45 mg (taken it divided into 2 days) was used for the fiver patient. If a malaria outbreak occurred, 4 days chemoprophylaxis need be adopted by choloriquine 1200 mg (taken it divded into 3 days) and primaquine 90 mg (taken it divided into 4 days) to the people where malaria outbreak. In the areas where malaria incidence was from 1 per ten thousand to 10 per ten thousand population, it could adopt 8 days medicine treatment (chloroquine 1200 mg+primaquine 180 mg) and nets treatment by deltamethrin.  In the area that malaria incidence was lower than 1 per ten thousands, 8 days medicine treatment (chloroquine 1200 mg+primaquine 180 mg) was used to the cure of patients.  Malaria incidences got a great drop by using the above strategies in the field during 2002-2006. Conclusion It would provide the science evidence for the establishment of vector control measure by the investigation of distribution rang, distribution characteristics and regularity of An.anthropophagus in Yunnan. The above control strategies in the areas with different incidences solved the key technical problem for the malaria control, which had appeared a good economic and social benefit during 2002-2006.

Key words: Anopheles anthropophagus, Malaria, Control strategy, Field application

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