中国媒介生物学及控制杂志 ›› 2009, Vol. 20 ›› Issue (3): 210-212.

• 论著 • 上一篇    下一篇

辛伐他汀抑制德国小蠊实验室种群发展的实验研究

冷培恩1,刘洪霞1,王士珍1,徐仁权1,何国声2,何璧梅3   

  1. 1 上海市疾病预防控制中心病媒生物防治科(上海  200336); 2 中国农业科学院上海兽医研究所;  3  四川抗菌素工业研究所
  • 收稿日期:2008-12-25 出版日期:2009-06-20 发布日期:2009-06-20
  • 作者简介:冷培恩(1963-),男,医学硕士,主任医师,科主任,从事媒介生物控制工作。

Study on the effect of simvastatin on the population dynamics of Blattella germanica in the laboratory

LENG Pei-En, LIU Hong-Xia, WANG Shi-Zhen, XU Ren-Quan, HE Guo-Sheng, HE Bi-Mei   

  1. Shanghai Center for Disease Control and Prevention, Shanghai  200336, China
  • Received:2008-12-25 Online:2009-06-20 Published:2009-06-20

摘要:

  【摘要】 目的 证实他汀类药物对德国小蠊种群的影响。方法 分别用0.001%辛伐他汀面饼和常规饲料饲喂德国小蠊,饲养不同时间后观察其种群中各虫态的数量及构成变化。结果 用0.001%辛伐他汀面饼饲喂试验组德国小蠊2、4、6和8个月后,其带鞘成虫数逐渐减少,相应的雌雄成虫数也逐渐减少。饲喂4个月后,试验组德国小蠊的若虫数为其在2个月时的2倍,但6个月后若虫数急剧下降,至8个月其雌虫数、带鞘成虫数均为0,雄性成虫数和若虫数分别为2只和15只。对照组正常饲养2个月和6个月后,带鞘成虫数高于最初投放数,但饲养4个月后,带鞘成虫总数略低于初始投放总数,8个月后基本与最初投放数持平。随着带鞘成虫数减少,雌雄成虫数逐渐减少,若虫数与实验组相似4个月时最高,以后逐渐减少,至8个月时尚有雌雄成虫数8只和12只,带鞘成虫数5只,若虫78只。 结论 0.001%辛伐他汀8个月能够使德国小蠊种群失去恢复能力。

关键词: 辛伐他汀, 德国小蠊, 种群恢复

Abstract:

  【Abstract】 Objective To verify the effect of simvastatin on the population dynamics of Blattella germanica. Methods Two groups of B.germanica were reared with feedstuff containing 0.001% simvastatin and common feed, respectively. The population quantity of different development stages of B.germanica and their constitution ratio were investigate after breeding for different time. Results The quantity of adult cockroaches with oothecae in the tested group reduced gradually after treatment for two months, six months and eight months, respectively. Accordingly, the quantity of male and female adult cockroach also decreased gradually. The nymphae quantity after treated for four months was two times than that after treatment for two months. However, it decreased rapidly in the sixth month, and the quantity of female adults and adults with oothecae reduced to zero in the eighth month. The quantity of male adults and nymphae was 2 and 15, respectively. The quantity of adults with oothscae was all higher than the initial number after they were bred with common feed for two months and six months. But in the forth month, it decreased a little compared to the initial number. And, it was basically equal to the initial number in the eighth month. With the decrease of the adults with oothecae, the quantity of male and female adults also reduced gradually. Similar to the tested group, the nymphae quantity in the control group was the highest after breeding for four month, and then it gradually decreased. In the eighth month, there were 78 nymphae, 5 adult cockroaches with oothacae, 8 female adults and 12 male adults. Conclusion B.germanica would lose the capability of its population restoration after breeding with feed containing 0.001% simvastatin for eighth months.

Key words: Simvastatin, Blattella germanica, Population restoration

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