关键词: 肾综合征出血热, 流行病学

Abstract: Aim Epidemic situation of HFRS have been investigated by author in Xianju County for 20 years.Method indirect immune fluorescent testing.Results Epidemic situation of sole peak appeared (epidemic situation increasing in stair-fashion before 1985,a peak in 1986,and decreasing year by year after 1988).Total cases of HFRS were 1 568 hitherto.The incidence of HFRS was 49.50 / 100 000 in 1986,which was the highest in the investigated years. The case of HFRS most of which were distributed in the shape of spot,was existing in all villages and towns.There was no evident relation among case of HFRS ,but there was a concentration relatively.Most of case were concentrated in the plain and hilly land of middle, lower reaches of YongAn brook. The type of both peak appeared in the distribution of season. The proportion of male to female was 1.89 ∶1. Young and robust people (at the age of 20-40) were 43.43 %, and the peasants were 88.01 % among all cases. In our county ,Apodemus agrarius Pallas and Rattus norvegicus Berkenhout were the main infectious sources of HFRS which appeared in focus of both family and wild types. It was demonstrated that the rate of recessive infection was 2.42 %, existing in the crowds of epidemic district. It was possible that leaked diagnosis of typical and atypical cases appeared in the season of HFRS. Conclusion It is suggested that examination of antigen of rats' lungs simultaneous with antibody of rats' sera were significant on epidemiology.