中国媒介生物学及控制杂志

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济南东郊秋冬型恙虫病流行病学研究

杨占清1; 刘运喜1; 孙海龙1; 于晓敏1; 孟祥瑞1; 冯茂全2   

  1. 1济南军区军事医学研究所 济南250014; 2中国建筑第八工程局
  • 出版日期:1998-08-20 发布日期:1998-08-20

Studies on the Epidemiology of Tsutsugamushi Disease of the AutumnWinterType in the Eastern Suburbs of Jinan

Yang Zhan-qing; Liu Yun-xi ; Sun Hai-long et al   

  1. Institute of Military Medicine,Jinan Command Jinan 250014
  • Online:1998-08-20 Published:1998-08-20

摘要: 目的:由于济南东郊历城区1988年10月首次发现恙虫病临床病例而开展流行病学调查。方法:采用斑点酶标染色法(IEA),检测患者、鼠类血清抗恙虫病立克次体(R.t);采用间接免疫荧光法(IFA),进行血清分型;同时进行病原分离。结果:有7个乡镇发生恙虫病流行,属秋冬型;流行季节储存宿主和传播媒介以黑线姬鼠和小盾纤恙螨为主;秋冬型恙虫病立克次体属弱毒株,接种小白鼠后无规律性死亡;从3组鼠类标本接种小白鼠的组织印片分离出R.t,血清抗R.t阳性。结论:血清学分型属Giliam型;疫源地属山地丘陵型。

关键词: 恙虫病, 秋冬型, 自然疫源地, 流行病学

Abstract: This paper reported that cases of tsutsugamushi disease was firstly found in the eastern suburbs of Jinan in October 1988,and has spread to 7 village communities ever since.The results showed that epidemical characterization differed greatly from those in southern regions.The major findings were as follows:Prevalence of tsutsugamushi disease belonged to the autumnwinter type;The main reservoir of infection were Apodemus agrarius;The transmitting vector was Leptotrombidium(L) scutellare;The pathogen of tsutsugamushi disease of the autumnwinter type belonged to lowvirulent strain,and inoculated mice could not regularly die from the infection;Rickettsia tsutsugamushi could be detected on tissular smears in 3 groups of mice inoculated with suspension of internal organs of mice,and specific antibodies could be detected in the sera;Serological typing of their sera showed that they belonged to the Gilliam type;Natural foci in Jinan could be divided into hilly land type.