关键词: 双甲敌鼠胺盐, 黄胸鼠, 褐家鼠, 适口性, 药效

Abstract: The Shashuxing was pnduced by Liaoning Institute of Chemical Industry.We determined the toxicity of Shashuxing with pouring oral method to rats.The values of acute and chronic oral LD₅₀ with 95% Confidence limit of Shashuxing were 104.69 (82.42 - 126.96), 3- 64 (2.82 - 4.46） mg/kg for R.flavipectus.The values of acute and chronic oral LD₅₀ with 95% confidence limit of Shashuxing were 15.80(12.27 - 19.33), 0.73 (0.57 - 0.89)mg/kg for _R.norvegicus.The feeding indes of R.flavipectus >0.6 to 0.05% and 0.1% Shashuxing baits, the feeding index of R.nondus> 0.7 to 0.025% and 0.05%Shasuxing baits in palatability test.The field trial against R.flavipectus was was carried out with 0.1% rice bait, the population decline was 92.4%.The field trial against R.norvegicus was carried out with 0.05% wheat bait, the population decline was 94.63%.The results showed the Shashuxing was well ghatable and Potent to R.flavipectus and R.norvegicus.It is worth the popularization and application in Yunnan.