中国媒介生物学及控制杂志 ›› 2010, Vol. 21 ›› Issue (4): 361-364.

• 技术方法 • 上一篇    下一篇

复配杀虫剂最佳增效配方的快速筛选及其计算机程序实现

裘炯良1, 郑剑宁1, 蒋雯音2   

  1. 1. 宁波出入境检验检疫局卫生检疫监管处(浙江宁波315012);
    2. 宁波天一职业技术学院
  • 收稿日期:2010-01-15 出版日期:2010-08-20 发布日期:2010-08-20
  • 作者简介:裘炯良(1975-),男,硕士,主要从事卫生检疫与传染性流行病学研究。Email: qiujl@nbciq.gov.cn

Rapid screening for the optimal synergistic formula for pesticide formulations and its program realization

QIU Jiong-liang1, ZHENG Jian-ning1, JIANG Wen-yin2   

  1. 1. Department of Health and Quarantine, Ningbo Inspection and Quarantine Bureau, Ningbo 315012, Zhejiang Province, China;
    2. Ningbo College of Health Sciences
  • Received:2010-01-15 Online:2010-08-20 Published:2010-08-20

摘要:

目的 采用国际通用的SAS统计分析平台编制计算机程序,实现复配杀虫剂最佳增效配方的快速筛选。方法 以朱砂叶螨为试虫,对A、B 2种药剂按一定比例复配后进行毒力测定及计算机程序演算,拟合质量分数反正弦变换值——共毒系数(CTC)的多项式数学模型,对模型曲线求导,计算最大CTC及最佳复配比例。结果 多项式数学模型有统计学意义(F=20.76,P<0.05),总决定系数(R2)=0.9540;模型方程:CTC=-2.021 499X2+222.543 940X-5951.467 969;曲线求导,计算得最佳极值X=55.04,对应的最大CTC=173.42,最佳复配比例为2∶1。结论 建立的快速筛选方法及编制的程序计算结果经双重验证,证明准确、可靠,且简便、快捷

关键词: 复配, 共毒系数, SAS, 数学模型

Abstract:

Objective A computer program was developed based on the internationally recognized statistics analysis system(SAS) to rapidly screen for the optimal synergistic formula for pesticide formulations. Methods Agents A and B were combined in a certain ratio and subject to the determination of toxicity against Tetranychus cinnabarinus and the computer program calculations for fitting the polynomial mathematical model of the co-toxicity coefficient (CTC), the arcsine transformation of the mass fraction. The derivative of the model curve was calculated and the maximum CTC and the optimal formulation ratio were computed. Results The polynomial mathematical model was statistically significant (F=20.76, P<0.05), the total coefficient of determination (R2)=0.9540; the model equation was: CTC=-2.021 499X2+222.543 940X-5951.467 969; the derivation of the curve revealed the best extreme value X=55.04, with the corresponding maximum CTC of 173.42 and the optimal formulation ratio of 2∶1. Conclusion Upon dual verification using program calculations, the established screening method proved to be an accurate, reliable, rapid and user-friendly approach to screen for the optimal synergistic formula.

Key words: Formulation, Co-toxicity coefficient, Statistics analysis system, Mathematical model

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