• 技术方法 •

### 复配杀虫剂最佳增效配方的快速筛选及其计算机程序实现

1. 1. 宁波出入境检验检疫局卫生检疫监管处(浙江宁波315012);
2. 宁波天一职业技术学院
• 收稿日期:2010-01-15 出版日期:2010-08-20 发布日期:2010-08-20
• 作者简介:裘炯良(1975-)，男，硕士，主要从事卫生检疫与传染性流行病学研究。Email: qiujl@nbciq.gov.cn

### Rapid screening for the optimal synergistic formula for pesticide formulations and its program realization

QIU Jiong-liang1, ZHENG Jian-ning1, JIANG Wen-yin2

1. 1. Department of Health and Quarantine, Ningbo Inspection and Quarantine Bureau, Ningbo 315012, Zhejiang Province, China;
2. Ningbo College of Health Sciences
• Received:2010-01-15 Online:2010-08-20 Published:2010-08-20

Abstract:

Objective A computer program was developed based on the internationally recognized statistics analysis system(SAS) to rapidly screen for the optimal synergistic formula for pesticide formulations. Methods Agents A and B were combined in a certain ratio and subject to the determination of toxicity against Tetranychus cinnabarinus and the computer program calculations for fitting the polynomial mathematical model of the co-toxicity coefficient (CTC), the arcsine transformation of the mass fraction. The derivative of the model curve was calculated and the maximum CTC and the optimal formulation ratio were computed. Results The polynomial mathematical model was statistically significant (F＝20.76, P＜0.05), the total coefficient of determination (R2)＝0.9540; the model equation was: CTC＝-2.021 499X2＋222.543 940X－5951.467 969; the derivation of the curve revealed the best extreme value X＝55.04, with the corresponding maximum CTC of 173.42 and the optimal formulation ratio of 2∶1. Conclusion Upon dual verification using program calculations, the established screening method proved to be an accurate, reliable, rapid and user-friendly approach to screen for the optimal synergistic formula.