中国媒介生物学及控制杂志

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1984至2002年山东省消灭丝虫病后丝虫病的监测分析

付兆义;桂建军;缪峰   

  1. 山东省寄生虫病防治研究所流行病学部 济宁272033
  • 出版日期:2006-04-20 发布日期:2006-04-20

Surveillance and Analysis of Filariasis in 19842002 After Elimination of Filariasis in Shandong Province

FU Zhao-yi; GUI Jian-jun; MIAO Feng   

  1. Shangdong Institute of Parasitic Diseasees,Jining 272033, China
  • Online:2006-04-20 Published:2006-04-20

摘要: 目的 监测山东省消灭丝虫病后丝虫病的流行情况。方法 系统阐述了1984~2002年丝虫病的监测结果。横向监测,采取病原学、媒介学、血清学、流动人口监测、晚期病人调查等方法。纵向监测,根据不同的地理方位及原丝虫病流行区发病率的高低,在全省各地共选择5个县5个乡(镇)18个行政村进行固定监测。结果 横向监测,在全省74个流行县(市、区)共调查502个乡(镇)1345个自然村,血检954467人,检出微丝蚴阳性者30例,阳性率为0.003%;媒介调查,共解剖淡色库蚊378816只,检出阳性蚊虫161只,自然感染率为0.04%;血清学调查,间接免疫荧光法(IFA)检测10667人次,丝虫抗体阳性者148例,阳性率为1.39%,接近非流行区人群水平;流动人口监测,在45个县(市、区)335个乡4473个村庄共血检36559人,检出微丝蚴阳性者147例,阳性率为0.40%。纵向监测显示,累计检出微丝蚴阳性者59例,全部在3~6年内自然转阴,蚊媒自然感染率为0.04%,并呈逐年下降趋势。结论 监测结果表明,各项指标均达到卫生部颁布的消灭丝虫病的标准。

关键词: 丝虫病, 横向监测, 纵向监测

Abstract: Objective To investigate and supervise the prevalence of filariasis after its elimination in Shangdong province. Methods From 1984 to 2002,Cross-sectional survey: survey of activity of permanent residents and mobile population,of mosquito vectors,of serum in human population,and of terminal patients were carried out. Longitudinal survey: according to different sites and the former incidence in these areas with the prevalence of filariasis,5 towns and 5 countries and 18 administrative villages were chosen to be under a fixed surveillance. Results Cross-sectional survey,502 towns and 1 345 villages were surveyed in 74 counties across the province,30 microfilarial positives cases of 954 467 people were found,and the positive rate is 0.003%; During the survey of vectors,378 816 Culex pipiens were dissected,161 positive mosquitoes were detected,the infection rate is 0.04%; In the survey of serology,10 667 cases were tested by indirect immunofluorescence assay(IFA),those with positive filarial antibody were 148,the positive rate was 1.39%,which was quite near to the level of that in non-prevalent areas; In the survey of mobile population,36 559 people were tested in 4 473 villages of 355 towns of 45 county,147 microfilarial positives were detected and the infection rate was 0.40%. The longitudinal survey showed that 59 microfilarial positives are detected in total,and all turn negative automatically within 3-6 years. The average infection rate of mosquitoes was 0.04%,and reduced year by year. 3 066 cases were tested by IFA,and with the positives 108,the average positive rate is 3.52%. Conclusion The results showed that all the indexes related to filariasis have come to the criterion of the elimination of filariasis issued by the ministry of health.