关键词: 肾综合征出血热, 暴发, 原因

Abstract: An outbreak of HFRS occurred in Yi An County,Heilongjiang Province in 1986,A total of 508 cases occurred,with a morbidity of 108.58/100000， and 23 casesdied, with a case fatality rate of 4.53%.There were 18 villages and towns in this County, of which 17( 94.44%) had occurrence of this disease. Although cases occurred sporadically, yet relatively concentrated.The number of cases in 4 villages and towns accounted for 78.54% of the total.The time of occurrence, age and sex were consistent with the data recorded in history.Two hundred and ninety patients were male with a morbidity of 120.83/100000；218 patients were female with a morbidity of 96.18/100000.The ratio of male to female was 1.33:1； the ratio of morbidity was 1.26:1.This was significantly different from the ratio(2.99:1) in data recorded in history of Heilongjiang Province(X²=1784.63, P＜0.005, X²=3219,P＜0.005）. The number of cases in the whole year had no relation with the density of rats（r=0.2314,n=9, P＞0.1）. However, it had relation with the density and constitutional percentage of Apodemus agrarius(r=0.7634,n=9, P＞0.005).When the constitutional percentage of Apodemus agrarius reached 40% or above，appearance of cases happened. The peak of the curve of this disease occurred in November, and the constitutional percentage of Apodemus agrarius reached 71.81%.Apodemus agra-rius was the main source of infection.