中国媒介生物学及控制杂志

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凤台县1982至1993年肾综合征出血热监测及分析

朱昌福; 余晨晓; 盛绍勤; 江传美   

  1. 安徽省凤台县卫生防疫站 232100
  • 出版日期:1995-04-20 发布日期:1995-04-20

Surveillance and Analysis on Hemorrhagic Fever with Renal syndrome (HFRS) in Fengtai County from 1982-1993

Zhu Chang-fu;et al   

  1. Fengtai County Hygiene and Epidemic Prevention Station,Anhui Pro vince 232100
  • Online:1995-04-20 Published:1995-04-20

摘要: 本文报道了凤台县1982~1993年肾综合征出血热人间疫情、兽间疫情监测及控制效果。自1957年治淮水利工程某工段发生首例病人以来,病例逐年增多,疫区逐渐扩大。1959~1993年共发病6924例,死亡141例,年均发病率由60年代的8.28/10万上升至80年代的80.64/10万,90年代前3年发病率为67.75/10万,病死率由1959年的40%、60年代的6.47%、80年代的1.59%降至90年代(前3年)的0.56%。疫区由初发的河湾湖洼地区逐渐扩大,现已波及全县所有乡镇。30多年来本病发生过4次较大流行,重疫区相对稳定,发病呈季节性高峰,以青壮年农民居多,男性略高于女性。患者恢复期血清抗体阳性率95.42%。健康人群隐性感染率1982~1990年为1.79%;而1991~1993年则为4.73%。黑线姬鼠和褐家鼠分别是野外及居民区优势种,构成比分别占80.49%和51.49%,其密度亦较高,与HFRS发病相关,并从黑线姬鼠和褐家鼠肺中检出HFRS病毒抗原。

关键词: 肾综合征出血热, 监测

Abstract: This article reports epidemics of HFRS in human and animals and the results of control and surveillance in Fengtai County from 1982 to 1993.Since the first case of HFRS occurred in Yuan Xing construction sector of the harness enginee-ring of the Huai River in 1957,cases gradually increased and epidemic areas gradually expanded.A total of 6 924 cases occurred from 1959 to 1993 with 141 deaths.The annual average morbidity rose from 8.28/100000 in 1960s to 80.64/100000 in 1980s, and the morbidity in the first three years of 1990s was 67.75/100000. The case fatality rate declined from 40% in 1959 to 6.47% in 1960s, 1.59% in 1980s and 0.56% in the first three years of 1990s.The epidemic areas gradually expanded from river wandering areas and lake low-lying areas to all villages and towns of the County.Four rather 1arge epidemics of HFRS have appeared in the past 30 or more years.Severe epidemic areas were relatively stable. The occurrence of this disease showed a seasonal peak. Adolescent and adult farmers were predominant.Male patie-nts_were more than female patients.The antibody-positive rate in convalecent sera was 95.42%.The inapparent infection rate among healthy population was 1.79% from 1982 to 1990, and 4.73% from 1991 to 1993. Apodemus agrarius and Rattus norvegicus were the predominant species of rats in fields and in residential areas, and their constitutional percantages were 80.49% and 51.49%,respectively.Their densities were high, related with the occurrence of HFRS. HFRS virus antigen had been detected from lungs of Apodemus agrarius and Rattus norvegicus.