基于不同媒介效能模型的簇鬃客蚤鼠疫媒介效能评价研究

岳锡宏, 史深, 袁江玲, 安冉, 徐佳丽, 赵国玉, 艾山·艾比布勒, 艾山江·哈得尔, 杨洪彩, 夏连续, 张渝疆

doi:10.11853/j.issn.1003.8280.2021.05.011

中国媒介生物学及控制杂志 >

2021 , Vol. 32 >Issue 5: 564 - 569

DOI: https://doi.org/10.11853/j.issn.1003.8280.2021.05.011

实验研究

基于不同媒介效能模型的簇鬃客蚤鼠疫媒介效能评价研究

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1. 新疆维吾尔自治区疾病预防控制中心消毒与感染控制中心, 新疆乌鲁木齐 830002;
2. 中国疾病预防控制中心传染病预防控制所, 北京 102206

岳锡宏,男,硕士,主任技师,从事特色实验动物开发工作,E-mail:406959660@qq.com

收稿日期: 2021-04-26

网络出版日期: 2021-10-20

基金资助

新疆维吾尔自治区创新环境（人才、基地）建设专项（PT1801）

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Plague transmission efficiency of Xenopsylla skrjabini based on the vector efficiency evaluation models

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1. Center for Disinfection and Infection Control, Xinjiang Uygur Autonomous Region Center for Disease Control and Prevention, Urumqi, Xinjiang 830002, China;
2. National Institute of Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China

Received date: 2021-04-26

Online published: 2021-10-20

Supported by

Supported by the Xinjiang Uygur Autonomous Region Innovation Environment (Talents, Bases) Construction Special Project (No. PT1801)

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摘要

目的评价簇鬃客蚤在不同媒介效能评级模型中的鼠疫传播效能。方法采用蚤类传播鼠疫的媒介效能实验技术方法获取簇鬃客蚤媒介效能指标，以Wheeler（1954）、Kartman（1956）和Macdonald修正的媒介效能模型计算簇鬃客蚤媒介效能。结果以Wheeler（1954）和Kartman（1956）的媒介效能模型评价，簇鬃客蚤的媒介效能为0.02；以Macdonald修正媒介传播流行病学模型评价的媒介效能为3.2，高于该模型判定支持动物鼠疫流行2.0的指标。结论蚤类的鼠疫媒介效能实验应以实验的目标为导向，采取适合的媒介效能实验方法和评价模型。簇鬃客蚤媒介效能指标显示，该蚤于自然生态条件下可在宿主动物间传播鼠疫。

关键词： 簇鬃客蚤; 媒介效能; Wheeler和Kartman模型; Macdonald模型

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岳锡宏, 史深, 袁江玲, 安冉, 徐佳丽, 赵国玉, 艾山·艾比布勒, 艾山江·哈得尔, 杨洪彩, 夏连续, 张渝疆 . 基于不同媒介效能模型的簇鬃客蚤鼠疫媒介效能评价研究[J]. 中国媒介生物学及控制杂志, 2021 , 32(5) : 564 -569 . DOI: 10.11853/j.issn.1003.8280.2021.05.011

Abstract

Objective To evaluate the plague transmission efficiency of Xenopsylla skrjabini in various vector efficiency evaluation models. Methods The vector efficiency index of X, skrjabini was acquired by the experimental method for plague transmission efficiency of fleas. The vector efficiency of X, skrjabini was calculated using the Wheeler (1954), Kartman (1956), and Macdonald-modified vector efficiency models. Results The vector efficiency of X, skrjabini was 0.02 based on the Wheeler (1954) and Kartman (1956) vector efficiency model, and 3.2 based on the Macdonald-modified vector efficiency model, which was higher than the reference value (2.0) for a plague epizootic based on the this model. Conclusion The experiment of plague transmission efficiency of fleas should be guided by the goal of the experiment, and adopt suitable vector efficiency experimental methods and vector efficiency evaluation models. The vector efficiency result of X, skrjabini indicates that this flea species can transmit plague among host animals under the natural zoological condition

Key words： Xenopsylla skrjabini; Vector efficiency; Wheeler and Kartman model; Macdonald model

参考文献

[1] Yang RF. Plague:recognition,treatment,and prevention[J]. J Clin Microbiol,2018,56(1):e01519-17. DOI:10.1128/JCM. 01519-17.
[2] 丛显斌,刘振才. 中国鼠疫及其防治(2001-2010)[M]. 长春:吉林科学技术出版社,2014:2-4.Cong XB,Liu ZC. Chinese plague and control[M]. Changchun:Jilin Science and Technology Press,2014:2-4.
[3] 张渝疆,戴翔,阿不力米提,等. 准噶尔盆地鼠疫调查[J]. 中华流行病学杂志,2008,29(2):136-144. DOI:10.3321/j.issn:0254-6450.2008.02.008.Zhang YJ,Dai X,Abulimiti,et al. Study on the situation of plague in Junggar basin of China[J]. Chin J Epidemiol,2008,29(2):136-144. DOI:10.3321/j.issn:0254-6450.2008.02.008.
[4] Zhang YJ,Dai X,Wang XH,et al. Dynamics of Yersinia pestis and its antibody response in great gerbils (Rhombomys opimus) by subcutaneous infection[J]. PLoS One,2012,7(10):e46820. DOI:10.1371/journal.pone.0046820.
[5] 张渝疆,阿扎提,雒涛,等. 准噶尔盆地鼠疫自然疫源地大沙鼠寄生蚤群落结构及其鼠疫流行病学分析[J]. 中华流行病学杂志,2013,34(11):1096-1100. DOI:10.3760/cma.j.issn.0254-6450.2013.011.012.Zhang YJ,Azati,Luo T,et al. Community structure of great gerbils(Rhombomys opimus) parasitic fleas in Junggar basin focus and related epizootiological characteristics on plague[J]. Chin J Epidemiol,2013,34(11):1096-1100. DOI:10.3760/cma.j.issn.0254-6450.2013.011.012.
[6] Zhang YJ,Dai X,Wang QG,etal. Transmission efficiency of the plague pathogen (Y.pestis) by the flea,Xenopsylla skrjabini,to mice and great gerbils[J]. Parasit Vectors,2015,8(1):256. DOI:10.1186/s13071-015-0852-z.
[7] 张渝疆. 基于自然生态模式的鼠疫媒介效能研究新思考[J]. 中华地方病学杂志,2017,36(6):391-394. DOI:10.3760/cma.j.issn.2095-4255.2017.06.001.Zhang YJ. A new thinking of the study on plague vector efficiency based on the natural ecological model[J]. Chin J Endemiol,2017,36(6):391-394. DOI:10.3760/cma.j.issn.2095-4255.2017. 06.001.
[8] 纪树立,贺建国,孙玺,等. 鼠疫[M]. 北京:人民卫生出版社,1988:186-187.Ji SL,He JG,Sun X,et al. Plague[M]. Beijing:People's Medical Publishing House,1988:186-187.
[9] Fine PEM. Epidemiological principles of vector-mediated transmission[M]//McKelvey JJ Jr,Eldridge BF,Maramorosch K,et al. Vectors disease agents. New York:Praeger,1981:77-91.
[10] Macdonald G. Epidemiologic models in studies of vector-borne diseases:the R. E. Dyer Lecture[J]. Public Health Rep,1961,76(9):753-764. DOI:10.2307/4591271.
[11] Eisen RJ,Eisen L,Gage KL. Studies of vector competency and efficiency of north American fleas for Yersinia pestis:state of the field and future research needs[J]. J Med Entomol,2009,46(4):737-744. DOI:10.1603/033.046.0403.
[12] Yang RF,Cui YJ,Bi YJ. Perspectives on Yersinia pestis:a model for studying zoonotic pathogens[M]//Yang RF,Anisimov A. Yersinia pestis:retrospective and perspective.Dordrecht:Springer,2016:377-391. DOI:10.1007/978-94-024-0890-4_14.
[13] 王启果,古丽阿依·包开西,雒涛,等. 簇鬃客蚤对宿主侵袭能力的实验观察[J]. 疾病预防控制通报,2013,28(5):1-3. DOI:10.13215/j.cnki.jbyfkztb.2013.05.019.Wang QG,Baokaixi G,Luo T,et al. Experimental observations on infestation ability of Xenopsylla skrjabini on hosts[J]. Bull Dis Control Prev,2013,28(5):1-3. DOI:10.13215/j.cnki.jbyfkztb. 2013.05.019.
[14] 热娜·吐尔地,布仁明德,戴翔,等. 新疆准噶尔盆地鼠疫菌生化和毒力测定[J]. 中国人兽共患病学报,2006,22(11):1086-1087. DOI:10.3969/j.issn.1002-2694.2006.11.022.Rena TED,Burenmingde,Dai X,et al. Biochemical and virulence determination of Yersinia pestis from Jungar basin in Xinjiang[J]. Chin J Zoonoses,2006,22(11):1086-1087. DOI:10.3969/j.issn.1002-2694.2006.11.022.
[15] Hinnebusch BJ,Jarrett CO,Bland DM. "Fleaing" the plague:adaptations of Yersinia pestis to its insect vector that lead to transmission[J]. Annu Rev Microbiol,2017,71:215-232. DOI:10.1146/annurev-micro-090816-093521.
[16] Hinnebusch BJ,Bland DM,Bosio CF,et al. Comparative ability of Oropsylla montana and Xenopsylla cheopis fleas to transmit Yersinia pestis by two different mechanisms[J]. PLoS Negl Trop Dis,2017,11(1):e0005276. DOI:10.1371/journal.pntd.0005276.
[17] Eisen RJ,Dennis DT,Gage KL. The role of early-phase transmission in the spread of Yersinia pestis[J]. J Med Entomol,2015,52(6):1183-1192. DOI:10.1093/jme/tjv128.
[18] Boegler KA,Graham CB,Johnson TL,et al. Infection prevalence,bacterial loads,and transmission efficiency in Oropsylla montana (Siphonaptera:Ceratophyllidae) one day after exposure to varying concentrations of Yersinia pestis in blood[J]. J Med Entomol,2016,53(3):674-680. DOI:10.1093/jme/tjw004.
[19] Dewitte A,Bouvenot T,Pierre F,et al. A refined model of how Yersinia pestis produces a transmissible infection in its flea vector[J]. PLoS Pathog,2020,16(4):e1008440. DOI:10.1371/journal.ppat.1008440.
[20] Webb CT,Brooks CP,Gage KL,et al. Classic flea-borne transmission does not drive plague epizootics in prairie dogs[J]. Proc Natl Acad Sci USA,2006,103(16):6236-6241. DOI:10. 1073/pnas.0510090103.
[21] Lorange EA,Race BL,Sebbane F,et al. Poor vector competence of fleas and the evolution of hypervirulence in Yersinia pestis[J]. J Infect Dis,2005,191(11):1907-1912. DOI:10.1086/429931.
[22] Bland DM,Jarrett CO,Bosio CF,et al. Infectious blood source alters early foregut infection and regurgitative transmission of Yersinia pestis by rodent fleas[J]. PLoS Pathog,2018,14(1):e1006859. DOI:10.1371/journal.ppat.1006859.
[23] Eisen RJ,Lowell JL,Montenieri JA,et al. Temporal dynamics of early-phase transmission of Yersinia pestis by unblocked fleas:secondary infectious feeds prolong efficient transmission by Oropsylla montana (Siphonaptera:Ceratophyllidae)[J]. J Med Entomol,2007,44(4):672-677. DOI:10.1093/jmedent/44.4.672.
[24] Wilder AP,Eisen RJ,Bearden SW,et al. Oropsylla hirsuta (Siphonaptera:Ceratophyllidae) can support plague epizootics in black-tailed prairie dogs (Cynomys ludovicianus) by early-phase transmission of Yersinia pestis[J]. Vector-Borne Zoonotic Dis,2008,8(3):359-368. DOI:10.1089/vbz.2007.0181.
[25] 王启果,孟卫卫,雒涛,等. 簇鬃客蚤生活史实验观察[J]. 中国媒介生物学及控制杂志,2012,23(1):35-38.Wang QG,Meng WW,Luo T,et al. Experimental observations of the life cycle of Xenopsyll askrjabini[J]. Chin J Vector Biol Control,2012,23(1):35-38.
[26] Wilder AP,Eisen RJ,Bearden SW,et al. Transmission efficiency of two flea species (Oropsylla tuberculata cynomuris and Oropsylla hirsuta) involved in plague epizootics among prairie dogs[J]. Ecohealth,2008,5(2):205-212. DOI:10.1007/s10393-008-0165-1.
[27] Enscore RE,Babi N,Amatre G,et al. The changing triad of plague in Uganda:invasive black rats (Rattus rattus),indigenous small mammals,and their fleas[J]. J Vec Ecol,2020,45(2):333-355. DOI:10.1111/JVEC.12404.
[28] 张晓雪. 有关中国跳蚤与鼠疫菌关系研究的进展[J]. 地方病译丛,1994,15(2):1-4.Zhang XX. Research progress on the relationship between fleas and Yersinia pestis in China[J]. Fore Endemic Dis,1994,15(2):1-4.
[29] Lemon A,Sagawa J,Gravelle K,et al. Biovar-related differences apparent in the flea foregut colonization phenotype of distinct Yersinia pestis strains do not impact transmission efficiency[J]. Parasit Vectors,2020,13(1):335. DOI:10.1186/s13071-020-04207-x.
[30] Bosio CF,Jarrett CO,Scott DP,et al. Comparison of the transmission efficiency and plague progression dynamics associated with two mechanisms by which fleas transmit Yersinia pestis[J]. PLoS Pathog,2020,16(12):e1009092. DOI:10.1371/JOURNAL.PPAT.1009092.

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