目的 掌握深圳市10个行政区的德国小蠊对常用杀虫剂的抗药性情况，了解抗性动态和发展规律，为蜚蠊的药物防制及制定有效的防控方案提供科学依据。方法 采用全国蟑螂防治学组制定的《蟑螂抗药性监测方案（试行）》规定的药膜法，取0.05%的药液2.5 ml置于500 ml透明广口瓶内，滚动广口瓶形成均匀药膜，放入德国小蠊雄性成虫，每隔一定时间观察和记录试虫的击倒情况，使用SPSS 24.0软件计算德国小蠊半数击倒时间（KT50）。结果 高效氯氰菊酯在龙岗区为高抗，抗性倍数为11.34倍，在宝安、光明和福田区为中抗，抗性倍数分别为8.79、8.77和8.07倍，其他地区均为低抗；氯菊酯在福田、龙华、宝安、龙岗和罗湖区为高抗，抗性倍数分别为22.26、13.99、14.28、13.01和10.01倍，在坪山区为中抗，抗性倍数为5.51倍，其他地区均为低抗；溴氰菊酯在宝安、龙岗和龙华区为中抗，抗性倍数分别为7.00、6.39和6.02倍，其他地区均为低抗；氯氰菊酯在宝安区为高抗，抗性倍数为19.65倍，在福田区为中抗，抗性倍数为9.42倍，其他地区均为低抗。而各行政区对毒死蜱、乙酰甲胺磷和残杀威均为低抗性。结论 深圳市德国小蠊对拟除虫菊酯类杀虫剂产生了不同程度的抗性，建议对中、高抗性的药物进行停用或限制使用，换用低抗性的毒死蜱、乙酰甲胺磷、残杀威等药物；同时应采取综合防治措施，控制和延缓德国小蠊抗药性的产生和发展。
Objective To investigate the resistance of Blattella germanica to commonly used insecticides in ten districts of Shenzhen, China and the dynamic development rules of such insecticide resistance, and to provide a scientific basis for the drug control of cockroaches and the formulation of effective prevention and control programs. Methods According to the residual film method in Cockroach insecticide resistance monitoring program (On trial) formulated by National Study Group of Cockroach Prevention and Control, 2.5 ml of 0.05% insecticide solution was placed into a 500 ml transparent wide-mouth bottle, and the wide-mouth bottle was rolled to form a uniform drug membrane. The male adults of B. germanica were put into the bottle, and the knockdown of the test insects was observed and recorded at a certain interval. SPSS 24.0 software was used to calculate median knockdown time. Results Beta-cypermethrin showed high resistance in Longgang district, with a resistance ratio of 11.34, medium resistance in Bao'an, Guangming, and Futian districts, with resistance ratios of 8.79, 8.77, and 8.07, respectively, and low resistance in the other districts. Permethrin showed high resistance in Futian, Longhua, Bao'an, Longgang, and Luohu districts, with resistance ratios of 22.26, 13.99, 14.28, 13.01, and 10.01, respectively, medium resistance in Pingshan district, with a resistance ratio of 5.51, and low resistance in the other districts. Deltamethrin showed medium resistance in Bao'an, Longgang, and Longhua districts, with resistance ratios of 7.00, 6.39, and 6.02, respectively, and low resistance in the other districts. Cypermethrin showed high resistance in Bao'an district, with a resistance ratio of 19.65, medium resistance in Futian district, with a resistance ratio of 9.42, and low resistance in the other districts. Chlorpyrifos, acephate, and propoxur showed low resistance in all districts. Conclusion Varying degrees of resistance to pyrethroid insecticides are observed in B. germanica in Shenzhen. It is suggested to stop or restrict the use of insecticides with medium and high resistance and to use chlorpyrifos, acephate, and propoxur with low resistance. At the same time, comprehensive control measures should be taken to control and delay the development and progression of insecticide resistance in B. germanica.
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