目的 探讨中国登革热重点疫区病例空间特征及相关关系。方法 采用空间可视化技术，分析2014－2018年广东和云南省登革热病例空间特征；采用Spearman相关分析法，探讨不同类型的登革热病例之间的相关关系。结果 研究区登革热病例主要集中在广东和云南省，2014－2018年间，本地病例、境外输入病例、境内输入病例和境内输出病例分别为46 306、2 304、79和625例。本地病例广东省广州市病例最多，达39 656例；境外输入病例云南省德宏傣族景颇族自治州（德宏州）瑞丽市病例最多，为1 640例，境外输入病例主要来自于东南亚，其中来自缅甸病例最多，达1 876例；境内输出病例主要来源于广州市，达457例，境内输出病例分布遍布中国南部省份。本地病例与境内输入病例、境内输出病例高度相关，相关系数分别为0.811和0.933。云南省德宏州瑞丽市本地病例与境外输入病例高度相关。结论 登革热病例集中在广东和云南省境内，本地病例与境内输入病例、境内输出病例高度相关，其研究结果有助于提供策略性的防控与预测方案，采取有效的登革热预防与控制措施。
Objective To explore the spatial characteristics and correlations of different types of dengue cases in key epidemic areas of dengue fever in mainland China. Methods Spatial visualization technology was used to analyze the spatial characteristics of dengue cases in Guangdong and Yunnan provinces from 2014 to 2018, and the Spearman correlation method was used to explore the correlations between different types of dengue cases. Results Dengue cases in the study area were mainly concentrated in Guangdong and Yunnan province from 2014 to 2018, there were 46 306 indigenous dengue cases, 2 304 overseas imported dengue cases, 79 domestically imported cases, and 625 domestically exported cases. Guangzhou of Guangdong province had the most indigenous cases (39 656). Ruili of Dehong Dai and Jingpo autonomous prefecture (Dehong prefecture) in Yunnan province had the most overseas imported cases (1 640). The main source of overseas imported cases came from Southeast Asia, the most of which came from Myanmar, reaching 1 876 cases. Domestically exported cases mainly came from Guangzhou, reaching 457 cases, which were distributed all over southern provinces of China. Indigenous cases were highly positively correlated with domestically imported cases and domestically exported cases, with coefficients of 0.811 and 0.933, respectively. In Ruili, Dehong prefecture, Yunnan province, the indigenous cases were highly correlated with overseas imported cases. Conclusion Dengue cases were concentrated in Guangdong and Yunnan provinces. Indigenous cases were highly correlated with domestically imported cases and domestically exported cases. The research findings are helpful for providing strategic prevention and control programs and taking effective measures for dengue prevention and control.
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