Objective To analyze the monitoring results of host animals of hemorrhagic fever with renal syndrome in Jingzhou, Hubei province, China from 2017 to 2018 for an understanding of the species, densities, and hantavirus-carrying situation of the host animals in the city. Methods From April to May (spring) of 2018 and from September to October (autumn) of 2017-2018, 1-2 villages each were selected from 8 counties (or cities/districts) of Jingzhou. Rodents were caught both indoors and in the field by the night trap method. The species of rodents were identified, and their lungs were taken for detection and classification of the nucleic acid of hantavirus by Real-time qPCR. Results From 2017 to 2018, the mean rodent density in Jingzhou was 7.02%, and the mean hantavirus-carrying rate was 13.37%. In spring, the indoor rodent density was 9.52%, and Mus musculus was the dominant species, among which no hantavirus was found; in the field, the highest density of 27.92% was in unharvested wheat fields, and Apodemus agrarius was the dominant species. The overall hantavirus-carrying rate was 12.64% in spring, and all the virus-positive A. agrarius rodents carried type I hantavirus and were captured in unharvested wheat fields. In autumn, the indoor density was 5.60%, and Rattus tanezumi was the dominant species, among which no hantavirus was found; in the field, the densities were higher in cabbage fields (12.33%), unharvested paddy fields (9.21%), and crayfish fields (5.99%), and A. agrarius was the dominant species. In autumn, the overall hantavirus-carrying rate was 13.62%; the virus-positive A. agrarius rodents carried type I hantavirus and were captured in cabbage fields and unharvested paddy fields; the virus-positive R. norvegicus carried type II hantavirus and were captured in crayfish fields and unharvested crayfish paddy fields. Conclusion In Jingzhou, the rodent density is relatively high in the indoor environment, where hantavirus is not detected; there are relatively high rodent densities and hantavirus-carrying rates in unharvested wheat fields during spring and in cabbage fields and unharvested paddy fields during autumn, and the virus-positive species are A. agrarius and R. norvegicus.
[1] Chan YC,Wong TW,Yap EH. Haemorrhagic fever with renal syndrome:clinical,virological and epidemiological perspectives[J]. Ann Acad Med Singapore,1987,16(4):696-701.
[2] Zou LX,Chen MJ,Sun L. Haemorrhagic fever with renal syndrome:literature review and distribution analysis in China[J]. Int J Infect Dis,2016,43:95-100. DOI:10.1016/j.ijid.2016.01.003.
[3] Zhao YL,Ge L,Zhou YJ,et al. A new seasonal difference space-time autoregressive integrated moving average (SD-STARIMA) model and spatiotemporal trend prediction analysis for hemorrhagic fever with renal syndrome (HFRS)[J]. PLoS One,2018,13(11):e0207518. DOI:10.1371/journal.pone.0207518.
[4] Xiang JJ,Hansen A,Liu QY,et al. Impact of meteorological factors on hemorrhagic fever with renal syndrome in 19 cities in China,2005-2014[J]. Sci Total Environ,2018,636:1249-1256. DOI:10.1016/j.scitotenv.2018.04.407.
[5] Ge L,Zhao YL,Zhou K,et al. Spatio-temporal pattern and influencing factors of hemorrhagic fever with renal syndrome (HFRS) in Hubei province (China) between 2005 and 2014[J]. PLoS One,2016,11(12):e0167836. DOI:10.1371/journal.pone.0167836.
[6] 刘红慧,刘天,邢学森. 2010-2017年湖北省肾综合征出血热流行特征及时空分布与发病趋势预测[J]. 疾病监测,2019,34(1):21-26. DOI:10.3784/j.issn.1003-9961.2019.01.007. Liu HH,Liu T,Xing XS. Epidemiological characteristics,spatial and temporal distribution and incidence trend of hemorrhagic fever with renal syndrome in Hubei,2010-2017[J]. Dis Surveil,2019,34(1):21-26. DOI:10.3784/j.issn.1003-9961.2019.01.007.
[7] 燕虹,王岳,刘力,等. 1971-2011年湖北省肾综合征出血热发病长期趋势分析[J]. 中国人兽共患病学报,2015,31(9):892-898. DOI:10.3969/j.issn.1002-2694.2015.09.022. Yan H,Wang Y,Liu L,et al. Long-term trend analysis of HFRS incidence in Hubei,China,1971-2011[J]. Chin J Zoonoses,2015,31(9):892-898. DOI:10.3969/j.issn.1002-2694.2015.09.022.
[8] 刘天,黄继贵,郝海波,等. 2017年荆州市HFRS流行病学特征及时空聚集性分析[J]. 现代预防医学,2018,45(15):2697-2701,2740. Liu T,Huang JG,Hao HB,et al. Epidemiological characteristics and temporal-spatial clustering analysis on HFRS in Jingzhou,2017[J]. Mod Prev Med,2018,45(15):2697-2701,2740.
[9] 刘天,姚梦雷,黄继贵,等. 荆州市肾综合征出血热流行特征及影响因素分析[J]. 现代预防医学,2018,45(12):2124-2127. Liu T,Yao ML,Huang JG,et al. Analysis on epidemiological features of hemorrhagic fever with renal syndrome and associated influencing factors in Jingzhou[J]. Mod Prev Med,2018,45(12):2124-2127.
[10] 刘天,黄继贵,郝海波,等. 湖北省荆州市2017年肾综合征出血热流行特征及宿主动物调查[J]. 中国媒介生物学及控制杂志,2018,29(6):609-612. DOI:10.11853/j.issn.1003.8280.2018.06.014. Liu T,Huang JG,Hao HB,et al. Epidemic situation of hemorrhagic fever with renal syndrome and investigation of the host animals in Jingzhou city of Hubei province in 2017[J]. Chin J Vector Biol Control,2018,29(6):609-612. DOI:10.11853/j.issn.1003.8280.2018.06.014.
[11] 王芹,李建东,张全福,等. 2014年全国肾综合征出血热监测总结和疫情分析[J]. 疾病监测,2016,31(3):192-199. DOI:10.3784/j.issn.1003-9961.2016.03.005. Wang Q,Li JD,Zhang QF,et al. Surveillance for hemorrhagic fever with renal syndrome in China,2014[J]. Dis Surveil,2016,31(3):192-199. DOI:10.3784/j.issn.1003-9961.2016.03.005.
[12] 姚苹苹,徐芳,朱函坪,等. 天台县汉坦病毒宿主动物调查及病毒分离结果[J]. 预防医学,2019,31(5):433-436,440. DOI:10.19485/j.cnki.issn2096-5087.2019.05.001. Yao PP,Xu F,Zhu HP,et al. The host investigation and virus isolation of hantavirus in Tiantai county[J]. Prev Med,2019,31(5):433-436,440. DOI:10.19485/j.cnki.issn2096-5087.2019.05.001.
[13] 胡泉博,陈淑红,孙巍,等. 黑龙江省2014-2016年肾综合征出血热宿主动物疫情监测研究[J]. 中国媒介生学及控制杂志,2019,30(3):278-280. DOI:10.11853/j.issn.1003.8280.2019.03.011. Hu QB,Chen SH,Sun W,et al. Monitoring of epidemic situation of host animals of hemorrhagic fever with renal syndrome in Heilongjiang province,China,in 2014-2016[J]. Chin J Vector Biol Control,2019,30(3):278-280. DOI:10.11853/j.issn.1003.8280.2019.03.011.
[14] 姚梦雷,刘天,黄继贵,等. 2005-2017年湖北省荆州市肾综合征出血热时空特征分析[J]. 疾病监测,2019,34(8):704-709. DOI:10.3784/j.issn.1003-9961.2019.08.007. Yao ML,Liu T,Huang JG,et al. Spatial-temporal distribution characteristics of hemorrhagic fever with renal syndrome in Jingzhou,Hubei,2005-2017[J]. Dis Surveil,2019,34(8):704-709. DOI:10.3784/j.issn.1003-9961.2019.08.007.
[15] Zhang YH,Ge L,Liu L,et al. The epidemic characteristics and changing trend of hemorrhagic fever with renal syndrome in Hubei province,China[J]. PLoS One,2014,9(3):e92700. DOI:10.1371/journal.pone.0092700.
[16] 宋干. 流行性出血热防治手册[M]. 2版. 北京:人民卫生出版社,1998:45-46. Song G. Epidemic hemorrhagic fever prevention manual[M]. 2nd ed. Beijing:People's Medical Publishing House,1998:45-46.
[17] 李明春,胡梦佳,刘金铭. 2008-2017年潜江市肾综合征出血热流行特征分析[J]. 公共卫生与预防医学,2019,30(2):65-68. DOI:10.3969/j.issn.1006-2483.2019.02.017. Li MC,Hu MJ,Liu JM. Epidemiological characteristics of hemorrhagic fever with renal syndrome in Qianjiang city (2008-2017)[J]. J Public Health Prev Med,2019,30(2):65-68. DOI:10.3969/j.issn.1006-2483.2019.02.017.
