目的 探讨鼠疫自然疫源地动物间鼠疫流行与主要宿主密度的关系。方法 分析1968－2018年河北省康保县康保牧场鼠疫监测数据，将鼠疫自然疫源地动物间鼠疫流行年份1～2年以及流行前3～4年共5年定义为1个流行单元，比较流行单元内主要宿主动物平均密度与总平均密度的差别。结果 3次流行单元内主要宿主动物密度分别为1.37、1.33和1.60只/hm²，明显高于总平均密度（0.92只/hm²）。结论 动物间鼠疫的流行随着主要宿主密度升高发生鼠疫的危险性增大。

Objective To investigate the relationship between plague epidemics among animals and the density of their main hosts in natural plague foci. Methods An analysis was conducted on the surveillance data of plagues in Kangbao Pasture in Kangbao county, Hebei province, China, from 1968 to 2018. An epidemic unit of 5 years was defined as 1 to 2 years during a plague epidemic and 3 to 4 years prior to the plague epidemic. Comparisons were carried out for the difference between the average density of main host animals and the overall average density in each epidemic unit. Results The density of main host animals in three epidemic units were 1.37, 1.33, and 1.60 animals/hm², respectively, which were significantly higher than the average density (0.92 animal/hm²) in the three epidemic units. Conclusion The risk of plague epidemics among animals increases with the density of main host animals.