目的 了解浙江省衢州市一起基孔肯雅热（CHIK）的流行特征，探索有效的防控策略，为今后防控工作提供依据。方法 对病例进行流行病学个案调查，采用实时荧光定量PCR检测患者血清中登革热病毒和基孔肯雅病毒（CHIKV）核酸，结合CHIK疫情流行情况，提出防控策略。结果 4例病例经实验室检测CHIKV核酸均为阳性，其中1例病例曾有孟加拉国旅行史，3例本地病例与首例病例同村居住，且无外出旅行史。经过实施病例搜索及疫点灭蚊等综合防控措施，该起疫情得到有效控制。结论 该起疫情是浙江省首起由输入性CHIK病例引起本地病例的案例，加强出入境检疫、开展医疗机构症状监测和控制传播媒介密度是预防控制CHIK的重要措施。
Objective To study the epidemic features of chikungunya fever outbreak in Quzhou and to explore the effective prevention and control strategies for this disease in the future. Methods All probable cases were chosen by epidemiological individual survey. Dengue and chikungunya virus nucleic acid testing were conducted by real-time quantitative reverse transcription polymerase chain reaction in individual survey. Results Among all samples tested 4 cases were positive for Chikungunya virus. One of the detected cases had a history of travel to Bangladesh. The remaining 3 local cases lived with the first confirmed case in the save village and had no travel record. The epidemic was efficiently controlled by case finding, mosquito eradication and ecological improvement, etc. Conclusion These are the first autochthonous cases reported that was caused by imported chikungunya fever in Zhejiang province. Enhanced entry-exit quarantine, case follow-up in clinical facilities, and vector surveillance are crucial for preventing epidemic of chikungunya.
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