目的 了解北京市不同城区德国小蠊对高效氯氰菊酯的抗性动态变化，为城区综合治理提供依据。方法 于2014和2016年每年的5-7月采集东城、西城、朝阳、昌平、密云、怀柔、大兴、石景山、顺义、房山和门头沟区的宾馆饭店、小旅馆、农贸市场和小餐饮店的德国小蠊种群，利用药膜法对其抗药性进行测定；采用SPSS 17.0软件计算半数击倒时间（KT₅₀）及其95% CI，并计算各种群的抗性倍数。结果 不同城区德国小蠊野外种群对高效氯氰菊酯抗性水平存在差异，东城、密云、怀柔、大兴、西城和昌平区野外种群对高效氯氰菊酯的抗性呈敏感性降低趋势，而石景山、朝阳、顺义、房山和门头沟区野外种群则呈敏感性升高趋势。除顺义区野外种群2014年抗性为中抗外，北京市11个区德国小蠊对高效氯氰菊酯的抗性均处于低抗水平，抗性倍数为1.01~5.14倍，其中东城和门头沟区野外种群抗性动态变化较大，东城区野外种群抗性倍数由2.39倍上升至4.44倍，门头沟区野外种群抗性倍数由4.58倍降至2.73倍。结论 2014和2016年北京市不同城区德国小蠊野外种群对高效氯氰菊酯抗性产生了不同程度的变化，各城区应根据抗性监测结果合理选用杀虫剂，采用综合防制方法，以延缓德国小蠊的抗药性发展。

Objective To understand the resistance dynamics of Blattella germanica to commonly used insecticide beta-cypermethrin, and provide the basis for the integrated pest management in different districts. Methods Insecticide resistance of 11 field strains B. germanica collected from hotels, gasthaus, farmer's markets, and small restaurants in Dongcheng, Xicheng, Chaoyang, Changping, Miyun, Huairou, Daxing, Shijingshan, Shunyi, Fangshan, and Mentougou district in 2014 and 2016, during May to July each year, were detected by surface contact method. The resistant ratio (RR) was calculated for each strain. Results The susceptibility of the field B. germanica strains to insecticide tested varied from different districts. The Dongcheng, Miyun, Huairou, Daxing, Xicheng, and Changping strains showed decreasing susceptibility to beta-cypermethrin, but Shijingshan, Chaoyang, Shunyi, Fangshan, and Mentougou strains showed increasing trend. The 11 field strains of B. germanica had low levels of resistance with RRs between 1.01 and 5.14 folds in 2014 and 2016 to beta-cypermethrin, except Shunyi strains with moderate resistance in 2014. The resistance change of Dongcheng and Mentougou stains was the widest, RR increased from 2.39 to 4.44 folds in Dongcheng strain, while RR decreased from 4.58 to 2.73 folds in Mentougou strain. Conclusion Field collected strains of B. germanica in different districts in Beijing had already developed different levels of resistance to beta-cypermethrin in 2014 and 2016. Based on the integrated pest management strategy, insecticides should be applied reasonably according to the local resistance surveillance results to control the cockroach effectively.