[1] Rivero A,Vézilier J,Weill M,et al. Insecticide control of vector-borne diseases:when is insecticide resistance a problem?[J]. PLoS Pathog, 2010, 6(8):e1001000.
[2] Nauen R. Insecticide resistance in disease vectors of public health importance[J]. Pest Manag Sci, 2007, 63(7):628-633.
[3] Zhu F,Lavine L,O' Neal S,et al. Insecticide resistance and management strategies in urban ecosystems[J]. Insects, 2016, 7(1):2.
[4] 王义平,吴鸿. 昆虫抗药性的分子机理研究进展[J]. 中国森林病虫, 2002, 21(5):34-36.
[5] Qiao CL,Sun ZQ,Liu JE. New esterase enzymes involved in organophosphate resistance in Culex pipiens (Diptera:Culicidae)from Guangzhou,China[J]. J Med Entomol, 1999, 36(6):666-670.
[6] Hall LM,Spierer P. The Ace locus of Drosophila melanogaster:structural gene for acetylcholinesterase with an unusual 5' leader[J]. EMBO J, 1986, 5(11):2949-2954.
[7] Sussman JL,Harel M,Frolow F,et al. Atomic structure of acetylcholinesterase from Torpedo californica:a prototypic acetylcholine-binding protein[J]. Science, 1991, 253(5022):872-879.
[8] Xu YC,Colletier JP,Weik M,et al. Long route or shortcut? A molecular dynamics study of traffic of thiocholine within the active-Site gorge of acetylcholinesterase[J]. Biophys J, 2010, 99(12):4003-4011.
[9] 冷欣夫. 杀虫药剂分子毒理学及昆虫抗药性[M]. 北京:中国农业出版社, 1996:319-320.
[10] Gao XW, Zhou XG, Wang RJ, et al. Distribution and purification of acetylcholinesterase in cotton boll worm (Lepidoptera:Noctuidae)[J]. Acta Entomol Sin,1998,41 Suppl:S19-25.
[11] Wu G, Miyata T. Susceptibilities to methamidophos and enzymatic characteristics in 18 species of pest insects and their natural enemies in crucifer vegetable crops[J]. Pestic Biochem Phys, 2005, 82(1):79-93.
[12] Cohen SG,Chishti SB,Beli DA,et al. General occurrence of binding to acetylcholinesterase-substrate complex in noncompetitive inhibition and in inhibition by substrate[J]. Biochim Biophys Acta, 1991, 1076(1):112-122.
[13] Bourne Y, Renault L, Essono S,et al. Molecular characterization of monoclonal antibodies that inhibit acetylcholinesterase by targeting the peripheral site and backdoor region[J]. PLoS One, 2013, 8(10):e77226.
[14] Vellom DC, Radić Z, Li Y, et al. Amino acid residues controlling acetylcholinesterase and butyrylcholinesterase specificity[J]. Biochemistry, 1993, 32(1):12-17.
[15] Barak D,Kronman C,Ordentlich A,et al. Acetylcholinesterase peripheral anionic site degeneracy conferred by amino acid arrays sharing a common core[J]. J Biol Chem, 1994, 269(9):6296-6305.
[16] Djogbénou L,Chandre F,Berthomieu A,et al. Evidence of introgression of the ace-1R mutation and of the ace-1 duplication in West African Anopheles gambiae s. s[J]. PLoS One, 2008, 3(5):e2172.
[17] Kim CS,Kim WT,Boo KS,et al. Cloning,mutagenesis,and expression of the acetylcholinesterase gene from a strain of Musca domestica; the change from a drug-resistant to a sensitive enzyme[J]. Mol Cells, 2003, 15(2):208-215.
[18] Liu HT,Stilwell G,Anthony N,et al. Analysis of a mosquito acetylcholinesterase gene promoter[J]. Insect Mol Biol, 1998, 7(1):11-17.
[19] Cherbas L,Cherbas P. The arthropod initiator:the capsite consensus plays an important role in transcription[J]. Insect Biochem Mol Biol, 1993, 23(1):81-90.
[20] Weill M,Malcolm C,Chandre F,et al. The unique mutation in ace-1 giving high insecticide resistance is easily detectable in mosquito vectors[J]. Insect Mol Biol, 2004, 13(1):1-7.
[21] Weill M, Lutfalla G,Mogensen K,et al. Comparative genomics:insecticide resistance in mosquito vectors[J]. Nature, 2003, 423(6936):136-137.
[22] Holt RA,Subramanian GM,Halpern A,et al. The genome sequence of the malaria mosquito Anopheles gambiae[J]. Science, 2002, 298(5591):129-149.
[23] 王敦,唐振华,尚金燕,等. 昆虫乙酰胆碱酯酶基因研究进展[J]. 昆虫学报, 2006, 49(3):497-503.
[24] Essandoh J,Yawson AE,Weetman D. Acetylcholinesterase (Ace-1) target site mutation 119S is strongly diagnostic of carbamate and organophosphate resistance in Anopheles gambiae s. s. and Anopheles coluzzii across southern Ghana[J]. Malaria J, 2013, 12:404.
[25] 惠圣铭,高菊芳. 基因扩增和昆虫抗药性[J]. 世界农药, 2012, 34(1):17-20.
[26] 吴明玮. 白纹伊蚊乙酰胆碱酯酶基因片段简并引物PCR、克隆及鉴定[D]. 广州:暨南大学, 2001.
[27] Labbé P,Berticat C,Berthomieu A,et al. Forty years of erratic insecticide resistance evolution in the mosquito Culex pipiens[J]. PLoS Genet, 2007, 3(11):e205.
[28] 周伯儒,卢慧甍,曹慧玲,等. 乙酰胆碱酯酶分子研究进展[J]. 生物技术通讯, 2012, 23(1):148-152.
[29] 何琳,喻红,邹晖,等. 抗药性基因突变筛选高产菌株[J]. 江西化工, 2004(4):169-171.
[30] Russell RJ,Claudianos C,Campbell PM,et al. Two major classes of target site insensitivity mutations confer resistance to organophosphate and carbamate insecticides[J]. Pestic Biochem Phys, 2004, 79(3):84-93.
[31] Smissaert HR. Cholinesterase inhibition in spider mites susceptible and resistant to organophosphate[J]. Science, 1964, 143(3602):129-131.
[32] Alout H,Berthomieu A,Cui F,et al. Different amino-acid substitutions confer insecticide resistance through acetylcholinesterase 1 insensitivity in Culex vishnui and Culex tritaeniorhynchus(Diptera:Culicidae)from China[J]. J Med Entomol, 2007, 44(3):463-469.
[33] Nabeshima T, Mori A, Kozaki T, et al. An amino acid substitution attributable to insecticide-insensitivity of acetylcholinesterase in a Japanese encephalitis vector mosquito,Culex tritaeniorhynchus[J]. Biochem Biophys Res Commun, 2004, 313(3):794-801.
[34] Edi CVA,Koudou BG,Jones CM,et al. Multiple-insecticide resistance in Anopheles gambiae mosquitoes,Southern Côte d' Ivoire[J]. Emerg Infect Dis, 2012, 18(9):1508-1511.
[35] Feng XY,Chan Y,Yang YC,et al. Distribution and frequency of G119S mutation in ace -1 gene within Anopheles sinensis populations from Guangxi, China[J]. Malaria J, 2015, 14:470.
[36] Liebman KA,Pinto J,Valle J,et al. Novel mutations on the ace-1 gene of the malaria vector Anopheles albimanus provide evidence for balancing selection in an area of high insecticide resistance in Peru[J]. Malaria J, 2015, 14:74.
[37] Ffrench-Constant RH,Pittendrigh B,Vaughan A,et al. Why are there so few resistance-associated mutations in insecticide target genes?[J]. Philos Trans R Soc B Biol Sci, 1998, 353(1376):1685-1693.
[38] Vaughan A,Rocheleau T,Ffrench-Constant R. Site-directed mutagenesis of an acetylcholinesterase gene from the yellow fever mosquito Aedes aegypti confers insecticide insensitivity[J]. Exp Parasitol, 1997, 87(3):237-244.
[39] Zhao MH,Dong YD,Ran X,et al. Point mutations associated with organophosphate and carbamate resistance in Chinese strains of Culex pipiens quinquefasciatus(Diptera:Culicidae)[J]. PLoS One, 2014, 9(5):e95260.
[40] Fournier D,Mutero A. Modification of acetylcholinesterase as a mechanism of resistance to insecticides[J]. Comp Biochem Physiol C, 1994, 108(1):19-31.
[41] Menozzi P, Shi MA, Lougarre A, et al. Mutations of acetylcholinesterase which confer insecticide resistance in Drosophila melanogaster, populations[J]. BMC Evol Biol, 2004, 4:4.
[42] 陈嘉,周志俊,顾祖维. 乙酰胆碱酯酶研究进展对更新有机磷毒作用机理的认识[J]. 劳动医学, 2001, 18(1):55-57.
[43] Alout H,Labbé P,Berthomieu A,et al. Novel AChE inhibitors for sustainable insecticide resistance management[J]. PLoS One, 2012, 7(10):e47125.
