目的 了解宁夏回族自治区（宁夏）银川、固原、吴忠和石嘴山市家蝇对5种卫生杀虫剂的抗药性状况。方法 2015-2016年在银川市兴庆区、固原市原州区、吴忠市利通区和石嘴山市大武口区的农贸市场、牲畜养殖场和垃圾场等地采集家蝇测定抗性。采用微量点滴法测定家蝇对杀虫剂的半数致死浓度（LD50）。结果 银川、固原、吴忠和石嘴山市的家蝇对5种卫生杀虫剂均产生了不同程度的抗药性，4个市对高效氯氰菊酯、溴氰菊酯、残杀威、DDT、毒死蜱5种杀虫剂的平均LD50值分别为0.1333、0.0678、2.0716、3.8104和0.1526μg/只，与文献报道的敏感品系试虫比较，其抗性倍数分别为26.66、135.60、48.74、381.04和5.09倍，DDT最高，毒死蜱最低。结论 亟需采取有效延缓家蝇抗药性的对策应用于灭蝇工作中。
Objective To investigate the susceptibility of Musca domestica to five kinds of insecticide from Yinchuan, Guyuan, Wuzhong and Shizuishan in Ningxia Hui Autonomous Region. Methods To investigate insecticides resistance of M. domestica from Xingqing of Yinchuan, Yuanzhou of Guyuan, Litong of Wuzhong and Dawukou of Shizuishan at farmers' markets, farm and dump sites from 2015 to 2016. The topical application method was used to determine the median lethal dose of M. domestica. Results Different degrees of resistance of M. domestica to five insecticides were observed in Yinchuan, Guyuan, Wuzhong and Shizuishan. The average LD50 to beta-cypermethrin, deltamethrin, propoxur, acephate and dichlorvos were 0.133 3, 0.067 8, 2.071 6, 3.810 4, and 0.152 6 μg/♀ in four cities. Compared with the susceptible strain reported in literature, the resistance ratio(R/S)were 26.66, 135.60, 48.74, 381.04, and 5.09 fold, DDT being the highest and dichlorvos the lowest. Conclusion It is necessary to take action to prevent the pesticide resistance in M. domestica.
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