目的 分析2006-2015年广州市恙虫病流行的时空分布特征，为疫情预报预警和防控提供时空线索支持。方法 搜集并整理广州市2006-2015年恙虫病病例数据，对该数据进行性别、职业和年龄分组频数统计分析，并计算其发病率，描述广州市恙虫病发病时间分布和人群分布；运用ArcGIS 10.3软件将该病发病率用地图形式加以展现，描述其空间分布特征。结果 2006-2015年广州市恙虫病年平均发病率为4.42/10万，发病月份集中在6-11月，占全年发病总数的74.61%；发病人群主要集中在50~岁年龄组，广州市城市外缘地区的发病率明显高于城市中心区。结论 广州市恙虫病发病率仍处于较高水平，并已形成明显的空间分布差异，应加强对高发区及高危人群的监测及防控。
Objective To analyze the spatiotemporal distribution of scrub typhus in Guangzhou city from 2006 to 2015, and provide the distribution information to the prevention and control of epidemic. Methods Data of scrub typhus cases from 2006 to 2015 were collected and used to analyze the prevalence by gender, occupation and age groups, calculate the incidence and describe the distribution of time and population. The spatial distribution characteristics were showed in the form of a map of the incidence by ArcGIS 10.3. Results The overall incidence rate of scrub in Guangzhou city from 2006 to 2015 was 4.42 per 100 thousand of human population. The cases were accounted intensively from June to November, and the highest incidence of scrub typhus concentrated in the age group of 50-59, The incidence in surroundings was significantly higher than that in center in Guangzhou. Conclusion Since 2006, the incidence of scrub typhus in Guangzhou city was rising and had obvious difference in space distribution. The monitoring in the high-risk areas and populations should be enhanced.
[1] Aung AK,Spelman DW, Murray RJ, et al. Rickettsial infections in Southeast Asia:implications for local populace and febrile returned travelers[J]. Am J Trop Med Hyg,2014,91(3):451-460.
[2] Ericsson CD, Jensenius M, Fournier PE, et al. Rickettsioses and the international traveler[J]. Clin Infect Dis,2004,39(10):1493-1499.
[3] 吴义城,李青华,张文义,等. 恙虫病流行特征及危险因素研究进展[J]. 公共卫生与预防医学,2015,26(2):70-74.
[4] Badenhorst D, Tatard C, Suputtamongkol Y, et al. Host cell/Orientia tsutsugamushi interactions:evolution and expression of syndecan-4 in Asian rodents (Rodentia:Muridae)[J]. Infect Genet Evol,2012,12(5):1136-1146.
[5] Jeong YJ, Kim S, Wook YD, et al. Scrub typhus:clinical, pathologic, and imaging findings[J]. Radiographics,2007,27(1):161-172.
[6] 李晓宁,黄勇,马钰,等. 广州市2010-2014年恙虫病流行特征及时空聚集性分析[J]. 中华疾病控制杂志,2016,20(4):345-348.
[7] 王铁强,姚云英,黄喜强,等. 2006-2012年广东省恙虫病流行特征分析[J]. 中华地方病学杂志,2014,33(4):429-432.
[8] 吴玮,王大虎,魏跃红. 2012年广州市恙虫病疫情分析[J]. 医学动物防制,2014,30(4):409-411.
[9] 刘运喜,赵仲堂,丰佩田,等. 北方秋冬型恙虫病新疫区儿童恙虫病临床特点及其流行因素[J]. 中华儿科杂志,2008,46(2):128-131.
[10] 廖云珍,叶晓光. 广州地区恙虫病流行病学和临床特征分析[J]. 中国热带医学,2013,13(6):709-712.
[11] 颜玉炳,郭志南,陈小平. 厦门市2010-2013年恙虫病流行特征及时空分布分析[J]. 中国社会医学杂志,2016,33(4):400-402.
[12] 胡文穗,李美霞,梁会营,等. 广州地区2006-2010年恙虫病流行病学特征分析[J]. 医学动物防制,2012,28(5):522-524.
[13] 何永辉,郑秀钰,李庆文,等. 2010-2014年三水区恙虫病流行特征[J]. 热带医学杂志,2016,16(1):111-112,122.
