目的 研究藻酸丙二醇酯及藻酸丙二醇酯与常用卫生杀虫剂混配药物对蜱的杀灭效果，以探索藻酸丙二醇酯作为蜱类杀虫剂的潜能。方法 将高效氯氰菊酯与藻酸丙二醇酯按照1：1、1：2和2：1的比例配成混液，与藻酸丙二醇酯、高效氯氰菊酯单品共同组成实验组，以相同量的水为对照组，对未吸血的长角血蜱幼蜱检测不同浓度在不同时间的杀灭效果。结果 低浓度藻酸丙二醇酯和低浓度的高效氯氰菊酯溶液（2.4 mg/L与250 mg/L）杀蜱效果相同（Mann-Whitney U=7，P=0.766）；高浓度的藻酸丙二醇酯和高浓度的高效氯氰菊酯溶液（12 mg/L与1 000 mg/L）杀蜱效果也相同（Mann-Whitney U=4，P=0.240）。早期（0.5 h）不同浓度的高效氯氰菊酯总杀蜱率优于藻酸丙二醇酯（χ²=7.670，P=0.007）。24及48 h藻酸丙二醇酯和高效氯氰菊酯的总杀蜱率差异无统计学意义（χ²=3.453，P=0.063；χ²=3.560，P=0.059）。混配液C（高效氯氰菊酯：藻酸丙二醇酯=2：1）各个浓度不同时间的杀蜱效果均优于混配液A（高效氯氰菊酯：藻酸丙二醇酯=1：1）、混配液B（高效氯氰菊酯：藻酸丙二醇酯=1：2）、藻酸丙二醇酯和高效氯氰菊酯溶液。结论 藻酸丙二醇酯对长角血蜱幼蜱有杀灭作用，但其杀灭作用并非速效型；高效氯氰菊酯与藻酸丙二醇酯混配比例以2：1为佳。

Objective To explore the lethal activity of propylene glycol alginate(PGA)and its mixed liquor with beta-cypermethrin against Haemaphysalis longicornis larvae, the aim was to evaluate the potential activity of PGA on killing ticks. Methods Mixed liquor was made with the ratio between beta-cypermethrin and PGA 1:1, 1:2, 2:1. Experimental group includes these three mixed liquor, PGA and beta-cypermethrin while the control is pure water. Spray tick larvae on culture dishes with these liquor, and then observed the mortality of ticks in different time series. Results There was no significance at any time series between high dilution of beta-cypermethrin(1 000 mg/L) and low dilution of PGA(12 mg/L) (Mann-Whitney U=7, P=0.766), and between high dilution of beta-cypermethrin(250 mg/L) and low dilution of PGA (2.4 mg/L) (Mann-Whitney U=4, P=0.240). However, the early efficiency(0.5 h) of PGA was significantly lower than beta-cypermethrin(χ²=7.670, P=0.007). The efficiency at 24 h and 48 h were the same between PGA and beta-cypermethrin(χ²=3.453, P=0.063; χ²=3.560, P=0.059). The efficient of mixed liquor C(ratio between PGA and beta-cypermethrin was 1:2) was the best of all. Conclusion PGA could kill the long-horned qinghaiensis ticks larvae, but it was not quick effect. According to the result, the most efficient ratio between beta-cypermethrin and PGA was 2:1.