目的 建立中华按蚊对常用杀虫剂的相对敏感基线。方法 中华按蚊引自中国疾病预防控制中心寄生虫病预防控制所,室内饲养50年以上,未接触任何杀虫剂。分别采用药液浸渍法和滤纸接触法测定幼虫和成蚊对常用杀虫剂的敏感度。结果 用药液浸渍法建立了溴氰菊酯、高效氯氰菊酯、氯菊酯、敌敌畏、仲丁威、杀螟硫磷和双硫磷7种杀虫剂对幼虫的敏感毒力基线,其结果分别为y＝13.0586＋3.8987x、y＝9.2950＋2.1510x、y＝10.3449＋4.4594x、y＝4.3319＋8.7669x、y＝11.3541＋11.2014x、y＝11.5447＋6.9681x、y＝10.8033＋4.6466x。用滤纸接触法建立了溴氰菊酯、高效氯氰菊酯、氯菊酯和仲丁威4种杀虫剂对成蚊的敏感毒力基线,其结果分别为y＝12.5204＋3.6871x、y＝10.2596＋3.0291x、y＝8.4266＋2.6610x和y＝13.8210＋5.0963x。结论 建立了7种常用杀虫剂对中华按蚊幼虫和4种常用杀虫剂对中华按蚊成蚊的敏感毒力基线,测定结果可以作为我国中华按蚊幼虫和成蚊区分剂量的参考值。

Objective To establish the susceptibility baselines of Anopheles sinensis to commonly used insecticides. Methods The An. sinensis was provided by the National Institute of Parasitic Diseases Control and Prevention, Chinese Center for Disease Control and Prevention, which was reared in the laboratory for more than 50 years without exposure to any pesticides. Impregnation method and filter paper contact method were used to determine the susceptibility to commonly used insecticides for the larvae and adults of An. sinensis. Results The susceptibility baselines of An. sinensis larvae to deltamethrin, beta-cypermethrin, permethrin, dichlorvos, BPMC, fenitrothion, and temephos were established by impregnation method; the results were described as y＝13.0586＋3.8987x, y＝9.2950＋2.1510x, y＝10.3449＋4.4594x, y＝4.3319＋8.7669x, y＝11.3541＋11.2014x, y＝11.5447＋6.9681x, and y＝10.8033＋4.6466x, respectively. The susceptibility baselines of adult An. sinensis to deltamethrin, beta?cypermethrin, permethrin, and BPMC were established by filter paper contact method; the results were described as y＝12.5204＋3.6871x, y＝10.2596＋3.0291x, y＝8.4266＋2.6610x, and y＝13.8210＋5.0963x, respectively. Conclusion The susceptibility baselines of An. sinensis larvae to seven insecticides and those of adult An. sinensis to four insecticides have been established. The results can be used as the reference for the discriminating doses for the larvae and adults of An. sinensis in China.