目的 了解新疆阿克苏地区沙雅县人间布鲁氏菌病(布病)疫情动态、流行规律,预测流行趋势和控制措施效果。方法 分层抽样选择6岁以上不同人群,对有可疑临床症状及接触密切的人群采血进行实验室检测。阳性率和患病率比较采用χ²检验。结果 个案调查4003人,血清学检测1903人,3年平均血检阳性率为1.52%,平均患病率为0.45%。兽医的血检阳性率和患病率均最高,分别为2.86%和2.36%。结论 羊是沙雅县布病传染源,有较高的疫情漏报,流行病学调查、血清学实验,采用试管凝集试验和平板凝集试验就可以满足调查目的。

Objective To investigate the epidemic situation, prevalence, epidemic trend, and control of human brucellosis in Shaya county of Aksu Prefecture, Xinjiang Uyghur Autonomous Region, China. Methods Different groups of people over 6 years of age were selected by stratified sampling in the study. Blood samples were collected from the individuals with suspicious clinical symptoms and in close contact with livestock to perform laboratory test. Positive rate and prevalence rate were compared between groups by chi-square test. Results A total of 4003 subjects were investigated, and 1903 of them underwent serological testing. Through three years, the mean positive rate in blood tests was 1.52%, and the mean prevalence rate was 0.45%. Veterinarians had the highest positive rate in blood tests (2.86%) and prevalence rate (2.36%). Conclusion Sheep is the source of infection of brucellosis in Shaya county. Omission of cases often occurs. Epidemiological investigation and serological testing can be performed by standard tube agglutination test and Rose Bengal plate test.