抗凝血类灭鼠剂抗性检测方法的研究概况

中国媒介生物学及控制杂志 ›› 2009, Vol. 20 ›› Issue (1): 88-90.

抗凝血类灭鼠剂抗性检测方法的研究概况

高志祥1，施大钊2，邱俊荣1，冯志勇1，姚丹丹1，隋晶晶1

1 广东省农业科学院植物保护研究所（广州 510640）； 2 中国农业大学

收稿日期:2008-07-25 出版日期:2009-02-20 发布日期:2009-02-20
通讯作者: 冯志勇，Email:fengzhy@tom.com
作者简介:高志祥（1982-），男，硕士，从事鼠害管理工作。

A survey of detection methods of anticoagulant rodenticide resistance

GAO Zhi-Xiang, SHI Da-Zhao, QIU Jun-Rong, FENG Zhi-Yong, YAO Dan-Dan, CUI Jing-Jing

Received:2008-07-25 Online:2009-02-20 Published:2009-02-20

摘要/Abstract

摘要：

　　【摘要】　及时、准确的抗性检测是合理使用抗凝血类灭鼠剂和有效应对害鼠形成抗性的关键。抗性检测方法目前有
3种，致死期食毒法（lethal feeding period, LFP）应用成熟，通过分析抗凝血剂抗性鼠和敏感鼠的数据确定98%（或99%）饲毒致死期（LFP98或LFP99）作为抗性检测标准；血凝反应法（blood clotting response, BCR）的原理是通过检测维生素K环氧化还原酶（VKOR）活性区分抗凝血剂抗性鼠和敏感鼠，也在广泛使用；基因检测法的研究方兴未艾，通过检测抗凝血剂抗性控制基因的突变情况来确定抗性，是目前最为准确和快捷的检测方法。3种方法都处在不断完善之中。

关键词: 抗凝血类灭鼠剂, 抗性检测, 致死期食毒法, 血凝反应法, 基因检测法

中图分类号:

S481+.4

高志祥1，施大钊2，邱俊荣1，冯志勇1，姚丹丹1，隋晶晶1. 抗凝血类灭鼠剂抗性检测方法的研究概况[J]. 中国媒介生物学及控制杂志, 2009, 20(1): 88-90.

GAO Zhi-Xiang, SHI Da-Zhao, QIU Jun-Rong, FENG Zhi-Yong, YAO Dan-Dan, CUI Jing-Jing. A survey of detection methods of anticoagulant rodenticide resistance[J]. Chines Journal of Vector Biology and Control, 2009, 20(1): 88-90.

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