Objective To assess the economic burden of dengue fever in Ningbo, Zhejiang province, China, 2018, and to provide a certain quantitative basis for the health administrative institution to formulate relevant prevention and control strategies. Methods Forty new cases of dengue fever were selected who were isolated and treated in a grade A tertiary hospital of Ningbo. Their information such as hospitalization process, treatment costs, indirect costs, and medical insurance reimbursement rate were collected to estimate the economic burden of dengue fever. Results The median length of hospitalization of the 40 cases was 8 (6-9) days. The economic burden of dengue fever was 3 718.16 (2 453.19-5 536.46) yuan per capita, with the direct economic burden of disease of 2 253.75 (767.16-3 606.54) yuan and the indirect economic burden of disease of 1 701.36 (1 432.72-1 813.29) yuan, indicating that the direct economic burden accounted for a large proportion. The total economic burden was about 260.30 (171.70-387.60) thousand yuan, with the direct economic burden of disease of 157.8 thousand yuan and the indirect economic burden of disease of 119.10 thousand yuan. Of the 40 dengue fever cases, 72.50% participated in medical insurance. The medical insurance reimbursement rate was negatively correlated with the direct medical economic burden, the direct economic burden of disease, and the economic burden of disease; the direct medical economic burden decreased as the reimbursement rate increased (P<0.05). Conclusion The economic burden of dengue fever in Ningbo is relatively high, the participation rate in medical insurance should be further increased to reduce the direct medical economic burden of patients.
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