中国媒介生物学及控制杂志 ›› 2012, Vol. 23 ›› Issue (4): 320-323.

• 论著 • 上一篇    下一篇

浙江省2008-2010年狂犬病流行特征分析

王玮, 柴程良, 孙继民, 王欣莹, 施旭光   

  1. 浙江大学公共卫生学院, 浙江省疾病预防控制中心, 浙江杭州 310051
  • 收稿日期:2012-02-25 出版日期:2012-08-20 发布日期:2012-08-20

Analysis on the epidemiological characteristics of rabies in Zhejiang province from 2008 to 2010

WANG Wei, CHAI Cheng-liang, SUN Ji-min, WANG Xin-ying, SHI Xu-guang   

  1. Zhejiang Center for Disease Control and Prevention, Hangzhou 310051, Zhejiang Province, China
  • Received:2012-02-25 Online:2012-08-20 Published:2012-08-20

摘要: 目的 根据2008-2010年浙江省狂犬病监测数据,总结狂犬病疫情流行病学特征,探讨狂犬病防控工作存在的问题,提出针对性措施。方法 收集2008-2010年浙江省犬伤门诊狂犬病监测和流行病学个案调查资料进行描述流行病学分析。结果 2008-2010年狂犬病发病呈逐年下降趋势。疫情扩散至浙江省中西部地区,衢州、金华等地发病率呈上升趋势。夏秋季为发病高峰,部分地区也表现出初冬第二高峰特征;职业构成以农民、民工和学生为主;3年性别比分别为3.2∶1、2.1∶1和2.1∶1;55~70岁中老年组发病人数最高,占39.71%。2008-2010年94例病例的致伤动物以犬为主,潜伏期中位数85 d ,潜伏期2个月至半年的最多,占35.11%;绝大多数病例暴露后未做任何处理(62.77%),部分仅自行简单消毒或冲洗(25.53%);暴露后接种狂犬病疫苗的有8 例(8.5%),其中仅1 例(1.06%)全程接种;病例中Ⅲ级暴露占67.02%,其中仅1例(1.06%)接受被动免疫制剂浸润。结论 建议改变狂犬病健康教育的目标人群和防制重点,倡导政府全额负担中老年人群的狂犬病暴露后处置费用。基层门诊工作人员亟需加强狂犬病相关培训,尤其是伤口处理和被动免疫制剂浸润等实际操作。

关键词: 狂犬病, 监测, 流行特征

Abstract: Objective To summarize the epidemiological characteristics of human rabies according to the surveillance data on rabies in Zhejiang province from 2008 to 2010, and explore the existing problems and the countermeasures. Methods The surveillance data on human rabies from the clinics and the epidemiological characteristics of individual cases in Zhejiang from 2008 to 2010 were collected for descriptive analysis. Results It was found that the incidence of rabies decreased from 2008 to 2010 year by year. The epidemic was spread to the central and western regions of Zhejiang, with the incidence rising in Quzhou and Jinhua. The peak incidence of rabies was seen in summer and autumn, with a second peak in early winter in some areas. Farmer, migrant workers and students were frequently affected. The sex ratio of the cases in the 3 years was 3.2∶1, 2.1∶1 and 2.1∶1, respectively. The number was highest in the age group of 55-70 years, accounting for 39.7%. Dogs were the principal reservoir of the 94 cases from 2008 to 2010. The incubation period was 85 d, with the period for the majority of the cases (35.11%) being between 2 months and half a year. The vast majority of cases after exposure did not receive any treatment (62.77%). Some of the cases after exposure were managed only with simple disinfection or flushing (25.53%). There were only 8.5% of the cases who received vaccination after exposure, of which only 1 case (1.06%) got full immunization with rabies vaccine. 67.02% of all the cases were classified as grade Ⅲ exposure and only one of them (1.06%) was administrated rabies immunoglobulin (RIG) or anti-serum. Conclusion It needs to change the target population of health education about rabies and the focus of control. Training of primary care staff should be strengthened in terms of knowledge related to rabies control, especially the interventions of wound management and infiltration of passive immunity preparations.

Key words: Rabies, Surveillance, Epidemiological characteristic

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