中国媒介生物学及控制杂志

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草原革蜱中肠抗原诱导宿主产生的对森林革蜱的交叉免疫抵抗

赵红斌1;杨银书2;史智勇1;第五进学2;李强2   

  1. 1兰州军区总医院兰州730050;2兰州军区军事医学研究所
  • 出版日期:2004-06-20 发布日期:2004-06-20

Hosts Induced by Midgut Antigens of Dermacentor nuttalli Producing Cross-immunological Resistance to Dermacentor silvarum

ZHAO Hong-bin*;YANG Yin-shu; SHI Zhi-yong; et al   

  1. GeneralHospital of Lanzhou Military Command,Lanzhou 730050,China
  • Online:2004-06-20 Published:2004-06-20

摘要: 目的了解草原革蜱中肠抗原诱导的免疫反应对森林革蜱的交叉抵抗力。方法用草原革蜱中肠抗原免疫家兔,然后用森林革蜱若虫和雌性成虫叮咬被免疫的家兔。结果森林革蜱若虫的平均吸血时间延长27.29h(0.01<P<0.05),对该蜱成虫的吸血时间影响无显著性(P>0.05),若虫蜕皮率减少26.7%(0.01<P<0.05),成虫产卵率减少41.1%(P<0.01),卵的孵化率减少19.0%(P<0.05)。结论草原革蜱中肠抗原诱导的免疫反应对森林革蜱具有明显的抵抗作用。

关键词: 草原革蜱, 森林革蜱, 中肠抗原, 交叉免疫

Abstract: Objective Studies were made on immunological reaction induced by Dermacentor nuttalli resisting Dermacentor silvarum.Methods Rabbits were immunized with midgut antigens of Dermacentor nuttalli and bitten by nymphae and female adults of Dermacentor silvarum.Results The average blood sucking time of nymphae was prolonged for 27.29 h ;the blood sucking time of adults was not affected obviously;exuviating rate of the nympha reduced to 26.7% ;oviposition rate of the adults reduced to 41.09%;hatching rate of the eggs reduced to 19.0%.Conclusion The immunological reaction induced by midgut antigens of Dermacentor nuttalli can resist Dermacentor silvarum evidently.