中国媒介生物学及控制杂志

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溴敌隆防制家栖鼠的实验室和现场评价

董天义1; 董民2; 常涛3; 王寿全4; 牛发祥5   

  1. 1军事医学科学院微生物流行病研究所 北京100071; 2北京88352部队门诊部; 3总后卫生部直属防疫队; 4二炮防护防疫环境监测队; 5总后勤部第一门诊部
  • 出版日期:2000-04-20 发布日期:2000-04-20

Efficacy of Anticoagulant Rodenticide Bromadiolone against Two Commensal Rodent Species

Dong Tianyi*; Dong Min; Chang Tao; et al   

  1. Institute of Microbiology and Epidemiology,Academy of Military Medical Sciences, Beijing 100071,China
  • Online:2000-04-20 Published:2000-04-20

摘要: 目的:评价溴敌隆防制家栖鼠的效果。方法:实验室毒力测定和摄食试验;现场灭鼠效果考核。结果:(1)溴敌隆对大白鼠的急性LD50和回归方程分别为0.86(0.80~0.92)mg/kg和Y=6.11+17.07x,慢性LD50和回归方程分别为0.16(0.15~0.18)×5mg/kg和Y=15.80+13.72x;对小白鼠的急性LD50和回归方程分别为1.19(1.01~1.27)mg/kg和Y=4.46+9.69x,慢性LD50和回归方程分别为0.22(0.20~0.25)×5mg/kg和Y=10.57+8.60x。(2)0.005%溴敌隆毒铒对大白鼠和小白鼠无选择和有选择摄食试验,都达到100%毒杀率;有选择试验的摄食系数分别为0.95和1.44。(3)现场试验,投毒饵7d灭鼠率66%,21d和35d灭鼠率分别为84%和95%。结论:溴敌隆对两种家栖鼠毒性强,适口性好,毒效高。

关键词: 抗凝血灭鼠剂, 溴敌隆, 毒力测定, 摄食试验, 现场灭鼠试验

Abstract: Laboratory and field trials were carried out to evaluate the effects of bromadiolone against Rattus norvegicus and Mus musculus. The acute and chronic oral LD50(CL) of the rodenticide were 0.86(0.80-0.92)mg/kg and 0.16(0.15-0.18)×5mg/kg for albino rats,and 1.19(1.01-1.27)mg/kg and 0.22(0.20-0.25)×5mg/kg for albino mice. Bromadiolone, at 0.005% in rice bait in 2 day no-choice and 4 day choice feeding tests in the laboratory caused 100% mortality of both albino strains, with a high palatable index 0.95 and 1.44 respectively. In a poultry farm heavy infested by R.norvegicus, using the same baits, the control rate reached 84% three weeks after treatment, and 95% five weeks after treatment. It is concluded that bromadiolone is a very effective rodenticide against rats and mice in the field use.