关键词: 传染病, 基因组, 大数据

Abstract: Objective To explore the management framework of genomic big data and to better serve infectious disease outbreak investigation and public health surveillance. Methods Scientific and legislative papers in the areas of genomic epidemiology and genomics in public health were extensively collected and reviewed. The Delphi method was used to consult experts on the summarization of the management factors and construction of information management platform. Results The collaborative management system including data management scheme, reagent and consumables information management platform and microbial genome database was constructed preliminarily. The reagent and consumables information management platform consisted of management department, laboratory department and company, which was connected to the genome database. It would keep data updated and shared in a timely manner. It could be 8-9 days faster than the traditional management model. The basic framework and functional division of the two platforms were drafted. It has set up to change its traditional extensive management and greatly improved the efficiency of scientific research. Conclusion The management of big genome data should be helpful to strengthen the management with informatization, standardization and specialization. It would provide statistical data for other projects, as well as audit department and enhance the service function.

Key words: Infectious disease, Genome, Big data