中国媒介生物学及控制杂志 ›› 2017, Vol. 28 ›› Issue (6): 535-537.DOI: 10.11853/j.issn.1003.8280.2017.06.005

• 论著 • 上一篇    下一篇

中国内地25例输入性寨卡病毒病病例流行病学与临床特征分析

王亚丽1, 张晓怡2, 任瑞琦1, 李超1, 向妮娟1, 涂文校1, 随海田1, 李剑森3, 张萌3, 陈恩富4, 王全意5, 刘晓青6, 胡建利7, 郭大城8, 倪大新1   

  1. 1 中国疾病预防控制中心, 北京 102206;
    2 桐乡市疾病预防控制中心, 浙江 桐乡 314500;
    3 广东省疾病预防控制中心, 广州 511430;
    4 浙江省疾病预防控制中心, 杭州 310051;
    5 北京市疾病预防控制中心, 北京 100013;
    6 江西省疾病预防控制中心, 南昌 330029;
    7 江苏省疾病预防控制中心, 南京 210009;
    8 河南省疾病预防控制中心, 郑州 450016
  • 收稿日期:2017-06-28 出版日期:2017-12-20 发布日期:2017-12-20
  • 通讯作者: 倪大新,Email:nidx@chinacdc.cn
  • 作者简介:王亚丽,女,研究员,从事传染病预防控制研究,Email:wangyl@chinacdc.cn;张晓怡,女,副主任医师,从事疾病预防控制研究,Email:zhangxiaoyi811121@163.com
  • 基金资助:
    国家重点研发计划(2016YFC1201000)

Epidemiological and clinical characteristics of 25 imported Zika cases in mainland China

WANG Ya-li1, ZHANG Xiao-yi2, REN Rui-qi1, LI Chao1, XIANG Ni-juan1, TU Wen-xiao1, SUI Hai-tian1, LI Jian-sen3, ZHANG Meng3, CHEN En-fu4, WANG Quan-yi5, LIU Xiao-qing6, HU Jian-li7, GUO Da-cheng8, NI Da-xin1   

  1. 1 Chinese Center for Disease Control and Prevention, Beijing 102206, China;
    2 Tongxiang Center for Disease Control and Prevention;
    3 Guangdong Center for Disease Control and Prevention;
    4 Zhejiang Center for Disease Control and Prevention;
    5 Beijing Center for Disease Control and Prevention;
    6 Jiangxi Center for Disease Control and Prevention;
    7 Jiangsu Center for Disease Control and Prevention;
    8 Henan Center for Disease Control and Prevention
  • Received:2017-06-28 Online:2017-12-20 Published:2017-12-20
  • Supported by:
    Supported by the National Basic Research Program of China(No. 2016YFC1201000)

摘要: 目的 了解中国内地25例输入性寨卡病毒病病例流行病学和临床特征,为寨卡病毒病防控工作提供参考依据。方法 2016年2月至2017年5月,收集中国内地25例输入性寨卡病毒病病例基本情况、流行病学暴露史、临床表现、实验室检测等信息进行描述性分析。结果 25例输入性病例输入来源国以委内瑞拉最多(17/25,占68.0%),年龄中位数为30岁,男女性别比为1.5∶1,职业分布以商业服务者最多(12/25,占48.0%),发现方式以入境检疫和健康随访发现较多(均为9例,各占36.0%)。所有病例均出现皮疹,出现结膜炎和发热的比例分别为64.0%及52.0%;病例标本实验室检测阳性率依次为尿液(92.0%)、唾液(80.0%)和血液(60.0%)。结论 加强对赴美洲等有寨卡病毒流行国家出境人员的健康教育,使其掌握寨卡病毒病防控知识;加强自疫情国家入境人员的检验检疫;皮疹、尿液阳性可作为诊断寨卡病毒病的重要依据。

关键词: 寨卡病毒, 输入性, 流行病学, 调查, 分析

Abstract: Objective To understand the epidemiological and clinical characteristics of 25 imported Zika cases in Mainland China, and to provide reference for the prevention and control of Zika disease. Methods Collect the information of 25 imported Zika cases in mainland China, and use descriptive study to analyze the characteristics of demography, epidemiology, clinic, and laboratory. Results Among 25 imported Zika cases, 17 cases (68.0%) came from Venezuela, the median age of all cases was 30, the ratio of male to female was 1.5:1, and half the number of cases (12/25, 48.0%) engaged in commercial services. The border quarantine and health follow-up were the main methods to discover the imported cases (each found 9 cases). All cases had skin rash, and the proportion of conjunctivitis and fever was 64.0% and 52.0%, respectively. In laboratory test, the positive rate of urine sample was 92.0%, followed by saliva sample (80.0%) and blood sample (60.0%). Conclusion Strengthening the health education for people who will enter the Americas and other epidemic countries, and consolidating the border screening and inspection of travelers from the Zika epidemic areas will help to prevent and control Zika in China. Skin rash and positive result of urine sample can be considered as important references to the diagnoses of Zika disease.

Key words: Zika virus, Imported, Epidemiology, Investigation, Analysis

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