中国媒介生物学及控制杂志 ›› 2014, Vol. 25 ›› Issue (4): 382-384.DOI: 10.11853/j.issn.1003.4692.2014.04.030

• 综述 • 上一篇    

家蝇金属硫蛋白的研究进展

赵志刚1,2,霍新北1,2,王学军1,2,康殿民1,景晓1,2,赖世宏1,张世水1,曲宝泉1   

  1. 1 山东大学预防医学研究院,山东省疾病预防控制中心,济南250014;
    2 山东省传染病预防控制重点实验室,济南250014
  • 收稿日期:2014-02-26 出版日期:2014-08-20 发布日期:2014-08-20
  • 作者简介:赵志刚,男,硕士,主管技师,从事病媒生物监测及控制研究,Email: zhgzh1982@163.com
  • 基金资助:
    山东省医药卫生科技发展计划项目(2009HW055)

Research advances in metallothionein inMusca domestica

ZHAO Zhi-gang1,2, HUO Xin-bei1,2, WANG Xue-jun1,2, KANG Dian-min1, JING Xiao1,2,LAI Shi-hong1, ZHANG Shi-shui1, QU Bao-quan1   

  1. 1 Shandong Center for Disease Control and Prevention,Institute for Preventive Medicine of Shandong University,Jinan250014,Shandong Province, China;
    2 The Key Laboratory for Infectious Diseases Prevention and Control in Shandong Province,Jinan250014,Shandong Province, China
  • Received:2014-02-26 Online:2014-08-20 Published:2014-08-20
  • Supported by:
    Supported by the Development of Medical Science and Technology Project of Shandong Province(No. 2009HW055)

摘要: 金属硫蛋白(MT)是一类广泛存在于生物体内的金属结合蛋白,富含半胱氨酸的小分子蛋白,能螯合多种金属离子,因其功能独特,近年来对MT各方面的研究日益受到重视。该文简述了家蝇MT的结构特点、理化性质和分布情况,以及参与体内解毒、清除自由基和微量元素代谢功能的研究现状及进展。

关键词: 金属硫蛋白, 家蝇, 功能, 研究进展

Abstract: Metallothioneins (MT) are a class of cysteine-rich, low-molecular-weight metal-binding proteins widely distributed in organisms, which can chelate various metal ions. In recent years, MT has been increasingly studied in different aspects due to its special functions. This paper briefly describes the structural characteristics, physical and chemical properties, and distribution ofMT and reviews the research advances in its participation in detoxication, free radical scavenging, and trace element metabolism.

Key words: Metallothionein, Musca domestica, Function, Research advance

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