关键词: 肾综合征出血热, 监测, 分析

Abstract: Objective To analyze the epidemiological characteristics of hemorrhagic fever with renal syndrome (HFRS) and the virus-carrying rate of host animals (rodents) in Tiantai county, Zhejiang province, China, and to provide a scientific basis for effective control of HFRS. Methods The data of the epidemic situation of HFRS in Tiantai were analyzed using descriptive epidemiological method. Rodents were captured using traps and then investigated. Indirect immunofluorescence assay was adopted to identify specific IgG antibody. Direct immunofluorescence assay was used to identify hantavirus antigen in the mouse lung. Results A total of 452 cases of HFRS were reported from 2001 to 2011 in the whole county, with 3 deaths, an annual average incidence of 7.27/10⁵, and a mortality rate of 0.66%. Throughout the whole county, the incidence of HFRS was primarily distributed in the towns and villages in the plain region at both sides of Shifeng River. This disease occurred in each month throughout the year, with May to July and October to December as high-incidence periods, accounting for 31.19% and 34.29% of all cases. People aged between 26-64 years were most easily infected, accounting for 86.06% of all cases. As for occupation, peasants constituted the majority of all cases, accounting for 82.52%. The ratio of male cases to female cases was 2.90:1. The coincidence rate of clinical diagnosis in these cases was 82.83%; the recessive infection rate of healthy population was 1.27%. The serological positive rate of mice was 5.20%. Apodemus agrarius was the dominating species in the field mice, followed by Rattus losea. R. norvegicus was dominant species in the house mice. The virus carrying rate of the mouse lung was 10.62%. Conclusion HFRS cases occurred every year in Tiantai county, Zhejiang province, China, and the virus carrying rate of host animals was relatively high. Measures should be taken to enhance surveillance and control of HFRS.

Key words: Hemorrhagic fever with renal syndrome, Surveillance, Analysis