我国基孔肯雅热的流行状况

中国媒介生物学及控制杂志 ›› 2011, Vol. 22 ›› Issue (3): 289-292.

我国基孔肯雅热的流行状况

张彦^1,2, 刘起勇¹

1 中国疾病预防控制中心传染病预防控制所，传染病预防控制国家重点实验室，北京 102206;
2 四川大学华西公共卫生学院流行病教研室，成都 610041

收稿日期:2010-11-25 出版日期:2011-06-20 发布日期:2011-06-20
通讯作者: 刘起勇，Email: liuqiyong@icdc.cn
作者简介:张彦（1985-），女，硕士研究生，从事病媒生物学与控制研究。Email: Jessica.yanzhang@gmail.com

Epidemic situation of chikungunya fever in China

ZHANG Yan^1,2, LIU Qi-yong¹

1 State Key Laboratory for Infectious Disease Prevention and Control, Department of Vector Biology and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China;
2 Department of Epidemiology, West China School of Public Health, Sichuan University, Chengdu 61004l, Sichuan Province, China

Received:2010-11-25 Online:2011-06-20 Published:2011-06-20

摘要/Abstract

摘要：

2010年10月，广东省东莞市暴发了我国首起基孔肯雅热社区聚集性疫情，打破了其长期以来以散在输入性病例为特征的流行现状。基孔肯雅热是一种由基孔肯雅病毒引起的急性传染病，伊蚊是其主要传播媒介。而我国大多数地区拥有其主要传播媒介埃及伊蚊和白纹伊蚊，一旦病原体侵入，可能暴发基孔肯雅热疫情。如何控制该疫情，防止疫情的进一步扩散，是摆在我们面前的当务之急。现就基孔肯雅病毒的病原学特征以及基孔肯雅热在我国历年的流行状况做一概述，以便更好地认识基孔肯雅热，为有效地监测和防治提供科学依据。

关键词: 基孔肯雅热, 病原学特征, 流行病学特征

Abstract:

In October 2010, China's first community-based chikungunya fever (CHIK) outbreak occurred in Dongguan, Guangdong, a deviation from the long-term predominance of sporadic imported cases. CHIK is an acute infectious disease caused by chikungunya virus (CHIKV) and mainly transmitted by Aedes aegypti and Ae. albopictus, which are widely distributed in China. A CHIK outbreak may occur following the invasion of CHIKV. Hence, it is urgent to formulate control measures to prevent further spread of this disease. This study gives an overview of the pathogenic and epidemiological characteristics of CHIK to promote understanding of this disease and improve surveillance, prevention and control programs.

Key words: Chikungunya fever, Pathogenic characteristics, Epidemiological characteristics

中图分类号:

R373.3

张彦, 刘起勇. 我国基孔肯雅热的流行状况[J]. 中国媒介生物学及控制杂志, 2011, 22(3): 289-292.

ZHANG Yan, LIU Qi-yong. Epidemic situation of chikungunya fever in China[J]. Chines Journal of Vector Biology and Control, 2011, 22(3): 289-292.

参考文献

[1] Karabatsos N. International catalogue of Arboviruses including certain othrc of vertebrates
[J]. Am Soc Trop Med Hyg,1985,3(71):327-328.

[2] 张海林. 基孔肯雅病研究现状和防制对策
[J]. 中国人兽共患病学报,2007,23(6):617-620.

[3] 刘春芳,司菡,陆家海. 基孔肯雅热的流行现况及其防治对策
[J]. 热带医学杂志,2009,9(4):463-466.

[4] Litzba N, Schuffenecker I, Zeller H, et al. Evaluation of the first commercial Chikungunya virus indirect immunofluorescence test
[J]. J Virol Methods,2008,149(1):175-179.

[5] Bréhin AC, Rubrecht L, Navarro-Sanchez ME, et al. Production and characterization of mouse monoclonal antibodies reactive to chikungunya envelope E2 glycoprotein
[J]. Virology,2008,371(1):185-195.

[6] Pialoux G, Gaüzère BA, Jauréguiberry S, et al. Chikungunya, an epidemic arbovirosis
[J]. Lancet Infect Dis,2007,7(5):319-327.

[7] 马素霞,郑晓燕,阴赦宏. 基孔肯雅热
[J]. 中国人兽共患病学报, 2008,24(2):167-169.

[8] Powers AM, Brault AC, Tesh RB, et al. Reccurrent arthralgisa in a patient with previous Mayaro fever infection
[J]. South Med J, 2005,98(4):484-485.

[9] Suhrbier A, La Linn M. Clinical and pathologic aspects of arthritis due to Ross River virus and other alphaviruses
[J]. Curr Opin Rheumetol,2004,16(4):374-379.

[10] Powers AM,Brault AC,Tesh RB,et al. Re-emergence of Chikungunya and O’nyong-nyong viruses: evidence for distinct geographical lineages and distant evolutionary relationships
[J]. J Gen Virol,2000,81(2):471-479.

[11] 黄文丽,张海林,侯宗柳,等. 云南西双版纳发热病人血清虫媒病毒抗体调查
[J]. 地方病通报,2001,16(2):29-30.

[12] 陈文州,李雪东,陈玉本,等. 海南岛虫媒病毒病血清学的初步调查
[J]. 华南预防医学,1985,26(4):77-79.

[13] 林苗,李华,黄吉城,等. 广东检验检疫局发现中国内地首例输入性基孔肯雅热病例
[J]. 中国国境卫生检疫杂志,2008,31(4): 221-223,236.

[14] 林苗,李华,戴俊,等. 口岸查验、实验室检测、快速联控三位一体构筑口岸防疫铜墙铁壁
[J]. 中国国境卫生检疫杂志,2009,32(5):293-296.

[15] 何展,吴文锋,杨适乡,等. 广东省茂名市首起输入性基孔肯雅热疫情调查
[J]. 疾病监测,2009,24(3):228-229.

[16] 黄仁杰,谢立,缪凡,等. 杭州发现1例输入性基孔肯雅热病例
[J]. 疾病监测,2009,24(4):303.

[17] 陈伯权,刘琴芝. 我国河北省一些地区人和猪血清的虫媒病毒抗体调查
[J]. 中华微生物学和免疫学杂志,1983,3(1):53-56.

[18] 张海林,施华芳,刘丽华,等. 从云南省蝙蝠中分离基孔肯雅病毒及血清抗体调查
[J]. 病毒学报,1994,5(1):31-36.

[19] 张海林,施华芳,米竹青,等. 云南基孔肯雅病调查研究
[J]. 中华实验和临床病毒学杂志,1994,8(2):161-164.

[20] 周淑新,刘莉. 亚洲再度浮现的基孔肯雅热
[J]. 中国全科医学, 2007,10(12):987-989.

[21] 杨海. 西安地区虫媒病毒血清流行病学调查
[J]. 职业与健康, 2001,17(5):82-83.

[22] 董必军,陈文州,李秀维,等. 首次从海南岛蚊虫和蝙蝠中分离出2株基孔肯雅病毒
[J]. 中国媒介生物学及控制杂志,1993,4(3):205-208.

[23] 张海林,自登云,米竹青,等. 云南白纹伊蚊分布特点及与虫媒病毒的关系
[J]. 中国媒介生物学及控制杂志,2001,12(2): 103-105.

[24] 张海林,米竹青,张云智,等. 白纹伊蚊和埃及伊蚊对基孔肯雅病毒的易感性和传播性的研究
[J]. 中国病毒学,1994,9(3):195-200.

[25] 陆宝麟. 50年来我国蚊媒研究进展
[J]. 中国媒介生物学及控制杂志,1999,10(3):161-165.

[26] 吴凡. 中国白纹伊蚊的分布和影响因素及登革热的风险评估研究
[D]. 北京:中国疾病预防控制中心,2010.

[27] 张天寿,王逸民,张永和,等. 云南西南边境地区人血清虫媒病毒抗体调查
[J]. 中华流行病学杂志,1989,10(2):74-77.

[28] 励峰,卢洪洲. 基孔肯雅热研究进展
[J]. 国际流行病学传染病学杂志,2007,34(4):240-242.

[29] Banerjee K, Mourya DT, Malunjkar AS. Susceptibility and transmissibility of different geographical strains of Aedes aegypti mosquitoes to Chikungunya virus
[J]. Indian J Med Res,1988,87: 134-138.

[30] Turell MJ, Beaman JR, Tammariello RF. Susceptibility of selected strains of Aedes aegypti and Aedes albopictus(Diptera: Culicidae) to Chikungunya virus
[J]. Meal Entomol,1992,29(1):49-53.

[31] 吴凡,刘起勇. 亚非暴发基孔肯雅病的流行特点
[J]. 中国媒介生物学及控制杂志,2007,18(6):527-529.

[32] Pages F,Corbel V,Paupy C. Aedes albopictus:chronical of a spreading vector
[J]. Med Trop (Mars),2006,66(3):226-228.