关键词: 氯敌鼠钠盐, 长爪沙鼠, 致死食毒期

Abstract:

【Abstract】　Objective　To determine the lethal feeding period (LFP) of 0.0025% Chlorophacinone baits in Meriones unguiculatus. Methods　A LFP?resistance?based detection method developed by the EPPO (European and Mediterranean Plant Protection Organization) was adopted. Results　The minimum lethal dose was 6.3510 mg/kg for M. unguiculatus, the highest survival dose 13.0230 mg/kg. Statistically significant differences were observed in the feeding period and its corresponding mortalities  between  male  and  female  groups (P＝0.036),  the  Probit  model (feeding  period  versus  mortality)  being  Probit (p)＝-2.651 95＋0.798 17x (P＝0.901),  and Probit(p)＝-5.620 58＋2.160 45x (P＝0.999), respectively. The LFP50, LFP98, LFP99 and  their  95%  confidence  limits(CI)  were  3.322 53 d(2.740 04-3.952 39),  5.895 58 d(4.939 49-8.323 31),  and  6.237 11 d (5.184 50-8.950 40) in  the  female  M. unguiculatus;  and  2.601 59 d (2.210 62-2.989 34), 3.552 20 d (3.115 84-5.024 47)  and  3.678 38 d (3.204 01-5.326 58) in the male  M. unguiculatus.  Conclusion　 In  LFP  resistance  detection  using  0.0025%  Chlorophacinone  baits  in M. unguiculatus, the 95%CI upper limit of LFP98, an integer number of days when applied as the drug?resistant testing standards, was 8 d for female rats and 5 d for males that survived in the feeding period; on the other hand, the 95%CI upper limit of LFP99, as an alternative, was 9 d for surviving female rats and 5 d for surviving males in the feeding period.

Key words: Chlorophacinone, Meriones unguiculatus, Lethal food poisoning phase