中国媒介生物学及控制杂志

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广东省家栖鼠对第一代抗凝血灭鼠剂抗药性研究

易建荣;林立丰;段金花;吴军;蔡松武;邹钦;张贤昌;阴伟雄;卢文成;陈文胜   

  1. 广东省疾病预防控制中心消毒杀虫研究所 广州510300
  • 出版日期:2006-12-20 发布日期:2006-12-20

Anticoagulant Rodenticide Resistance in Commensal Rodents in Guangdong

YI Jian-rong; LIN Li-feng; DUAN Jin-hua; WU Jun; CAI Song-wu; ZOU Qin; ZHANG Xian-chang; YIN Wei-xiong; LU Wen-cheng; CHEN Wen-sheng   

  1. Center for Diseases Control and Prevention of Guangdong Province, Guangzhou 510300, China
  • Online:2006-12-20 Published:2006-12-20

摘要: 目的 探讨广东省家栖鼠对抗凝血灭鼠剂的抗药性变化。方法 按全国鼠类抗药性监测协作组统一方法,进行无选择性摄毒试验。结果 经对广东省5市所捕捉的769只褐家鼠、303只黄胸鼠进行抗药性监测,其抗性率分别为1.69%和12.21%,总平均摄药剂量分别为10.36和131.96mg/kg,按家栖鼠抗药性检验标准,黄胸鼠和褐家鼠均对第一代抗凝血剂杀鼠灵产生抗药性个体。结论 以黄胸鼠为优势种的场所,要考虑使用第二代抗凝血灭鼠剂;而以褐家鼠为主的场所,则可继续使用第一代抗凝血灭鼠剂,同时应加强对灭鼠药物的敏感性监测,科学、合理用药。

关键词: 家栖鼠, 抗凝血灭鼠剂, 杀鼠灵, 抗药性

Abstract: Objective To study the resistance development of anticoagulant rodenticide in commensal rodents. Methods Tests was carried out without selectivity by rodents based on the method of National Rodenticide Resistance Monitoring Co-worker Group. Results 769 Rattus flavipectus and 303 Rattus norvegicus were caught in five cities of Guangdong were tested. The resistance rate differs from 1.69 to 12.21 the average dosage taken differs from 10.36 mg/kg to 131.96 mg/kg . The result showed that Rattus flavipectus and Rattus norvegicus had become individual resistance to the resistance rodenticide Ⅰ. Conclusion The anticoagulant rodenticide Ⅱ should be used in the areas gathered with Rattus flavipectus. The anticoagulant rodenticide Ⅰ can be still used but should be used scientifically and properly with careful tests of sensitivity.