中国媒介生物学及控制杂志

• 论著 • 上一篇    下一篇

清远市家栖鼠对第一代抗凝血灭鼠剂抗药性研究

易建荣1;黄亿初2;吴军1;张世炎3;蔡松武1;段金花1;阴伟雄1;林立丰1   

  1. 1广东省疾病预防控制中心消毒杀虫研究所 广州5103000;2清远市爱卫办;3广东省湛江鼠疫防治研究所
  • 出版日期:2005-08-20 发布日期:2005-08-20

Study on the Resistance of Commensal Rodents to Anticoagulant Rodenticide in Qingyuan,Guangdong

YI Jian-rong*; HUANG Yi-chu; WU Jun; et al   

  1. Center for Diseases Control and Prevention of Guangdong Province, Guangzhou 510300, China
  • Online:2005-08-20 Published:2005-08-20

摘要: 目的 探讨家栖鼠对抗凝血灭鼠剂的抗药性变化。方法 按全国鼠类抗药性监测协作组统一方法,进行无选择性摄毒试验。结果 经对清远市城区及所辖3个县城区内所捕获的155只褐家鼠、13只黄胸鼠、28只小家鼠进行抗药性监测,其抗性率分别为0.65%、0和50.00%,总平均摄药剂量分别为9.82、84.92和453.70mg/kg,按家栖鼠抗药性检验标准,小家鼠对第一代抗凝血剂杀鼠灵已形成抗药性种群,褐家鼠有抗药性个体产生。结论 以小家鼠为优势种的场所,要考虑使用第二代抗凝血灭鼠剂;而以褐家鼠、黄胸鼠为主的场所,则可继续使用第一代抗凝血灭鼠剂,但应加强对灭鼠药物的敏感性监测,科学、合理用药。

关键词: 家栖鼠, 抗凝血灭鼠剂, 杀鼠灵, 抗药性, 监测

Abstract: Objective To study the resistant development of anticoagulant rodenticide in commensal rodents. Methods Unselective feeding method was used,which was established by "Rodenticideresistance Monitoring Cooperation Group in China" in 1985. Results The rodents (155 Rattus norvegicuus,13Rattus flavipectus and 28 Mus musculus) caught in Qingyuan and it's three county city zone of Guangzhou province were tested. The resistance rate differs from 0.65%?0 to 50.00% for Rattus norvegicus,Rattus flavipectus and Mus musculus with average taken dosages 9.82,84.92 to 453.70 mg/kg respectively. The result shows that Mus musculus have developed resistance to anticoagulant rodenticide Ⅰ and Rattus norvegicus has individual resistance. Conclusion The resistance rodenticide Ⅱ should be used in the areas Mus musculus more than others. The anticoagulant rodenticide Ⅰ can be still used but should be used scientifically and properly with careful tests of sensitivity.