关键词: 小肠结肠炎耶尔森菌, 毒力基因

Abstract: Objective To investigate the contribution of virulence factors of common pathogenic Yersinia serotypes in China.Methods Developed PCR technology described by other authors was used to detect the virulence factors.Results The contribution characters of the main Yersinia serotypes O∶3 and O∶9 in China were ail⁺,yst⁺,ystB^-,yadA⁺,virF⁺( 56.2%);ail⁺,ystA⁺,ystB^-,yadA^-,virF ^-( 25.6%),other serotypes were 18.2%.Conclusion It was confirmed that the main virulence factors that caused Yersinia enterocolitis outbreak and epidemics in China were ail⁺,ystA⁺,ystB^-,yadA⁺,virF ⁺.The minor parts were ail⁺,ystA⁺,ystB^-,yadA^-,virF ^-,which were considered the result of lost of virulent plasmid at the past time.Other serotypes maybe the non-pathogenic strains.