关键词: 球形芽孢杆菌, 致倦库蚊, 杀蚊毒性, 抗性

Abstract: Bacillus sphaericus C_3-41 larvicidal formulation has been continuously used to control Culex quinquefasciatus larvae for eight years in Dongguan, Guangdong .It has proved that this kind of formulation has high efficacy against the target larvae in early treatment period. Under the high continuous selective pressure,C.quinquefasciatus developed very high resistance to C_3-41 and the resistance level was calculated to be 24 545-fold in comparison with the sensible larvae collected from the untreated areas. It also showed that the B.sphaericus LP1-G had the same toxicity against both susceptible and resistant larvae and B.thuringiensis subsp. israelensis was more active to the former than the latter.So we suggested B.thuringiensis israelensis could be used as a promising alternative for controlling the resistant larvae.