中国媒介生物学及控制杂志

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粤东地区莱姆病血清流行病学调查

郭衍1; 万康林2; 许世锷1; 陈慎奔1; 潘林祥3; 张哲夫2; 王宏英2; 廖传红1; 谢霖崇1; 陈贵友3; 邓经谋3; 姚良治3   

  1. 1汕头大学医学院515031; 2中国预防医学科学院流行病学微生物学研究所; 3广东省梅州市卫生防疫站
  • 出版日期:1998-08-20 发布日期:1998-08-20

Investigation on the Lyme Disease Populated in the Eastern Part of Guangdong Province (Three Counties in Meizhou City)

Guo Yan*; Wan Kang-lin; Xu shi-e; et al   

  1. Medical College Shantou University 515031
  • Online:1998-08-20 Published:1998-08-20

摘要: 目的:检测健康人群血清莱姆病抗体水平。方法:间接免疫荧光抗体试验(IFA)、酶联免疫吸附试验(ELISA)。结果:共检测2184人,阳性225人,感染率10.30%。儿童(13.85%)、学生(11.93%)感染率最高,农民(10.57%)次之,林业工人及管理人员(6.44%)相对较低;林区(10.37%)与非林区(10.27%)人群感染率差异无显著性(χ2=0.21,P>0.75)。180例莱姆病血清阳性者中,蜱叮咬率为40%,未发现典型的慢性游走性红斑(ECM)皮疹患者,红斑、风团、紫斑占32.78%,肌痛占23.33%,关节炎占41.11%。结论:粤东地区人群莱姆病感染率较高。

关键词: 莱姆病, 血清学, 个案调查

Abstract: Using IEA and ELISA, we examined the antibodies of Lyme disease populated in the eastern part of Guangdong province in 1994-1995 (three counties in Meizhou city). Of 2184 investigated people, 225 cases were infected, the rate of infection was 10.30%.The highest infection was in children, pupils, the second was peasants. The infective rate seems relatively lower among the workers and the administractive personel of the forest.There were no obvious differences in the population between the forest and the noforest area.In the individual investigation on the 180 antibody positive cases, we found 40.00% of them bitten by ticks, no typical ECM rash, 32.78% of them had specks, urticaria (nettle rash), purple specks, 23.33% muscle pain, 41.11% arthritis.The investigation proved the Lyme disease was present in the eastern part of Guangdong province, the subtropical area, the infective rate be high.