从须纤恙螨分离到恙虫病立克次体的研究

中国媒介生物学及控制杂志

从须纤恙螨分离到恙虫病立克次体的研究

刘运喜1; 吴钦永1; 孙海龙1; 杨占清1; 孟祥瑞1; 张海莲2; 苏明3; 张学林3

1济南军区军事医学研究所250014; 2北京生物制品研究所; 3解放军五四八九四部队卫生队

出版日期:1998-02-20 发布日期:1998-02-20

First Isolation of Rickettsia Tsutsugamushi from Leptotrombidium Palpalis

Liu Yun-xi; Wu Qin-yong; Sun Hai-long; et al

Medical Institute of Jinan Military Command, PLA,Jinan,250014

Online:1998-02-20 Published:1998-02-20

摘要/Abstract

摘要： 目的：研究纤须恙螨的恙虫病病原学意义及潜在媒介作用。方法：以71～150只左右须纤恙螨为一批接种小白鼠，共分4批。结果：均成功地分离到恙虫病立克次体。传代小鼠的临床症状有弓背、耸毛、厌食等，内脏仅见肝脏肿大，脾脏只在最初2代有个别肿大。IFA法检测传代阳性小鼠血清中的恙虫病立克次体IgG抗体，均呈阳性反应，血清分型结果均为Giliam型。对须1104株LD₅₀测定结果为10^－1.4375。结论：须纤恙螨是仅作为恙虫病立克次体的宿主，抑或既是宿主又可充当潜在媒介，在恙螨→人或恙螨→鼠之间起作用，值得进一步研究。

关键词: 须纤恙螨, 恙虫病立克次体分离

Abstract: This article reported the isolation of Rickettsia tsutsugamushi (Rt.) from Leptotrombidium palpalis in China for the first time.4 strains were obtained from 4 groups of chiggers (71-150 chiggers as a group).Enlargement of liver was observed in experimented mice inoculated with isolates, but the spleen′s enlargement was rarely observed.Serological identification of 4 strains revealed strong positive reaction with Rt.(Gilliam strain).More research was needed to confirm whether L.palpalis can act as a vector of Rt.from chiggers to rodents or from chiggers to men.

刘运喜1; 吴钦永1; 孙海龙1; 杨占清1; 孟祥瑞1; 张海莲2; 苏明3; 张学林3. 从须纤恙螨分离到恙虫病立克次体的研究[J]. 中国媒介生物学及控制杂志.

Liu Yun-xi; Wu Qin-yong; Sun Hai-long; et al. First Isolation of Rickettsia Tsutsugamushi from Leptotrombidium Palpalis[J]. Chines Journal of Vector Biology and Control.

[1]	佘建军1; 张云2; 黄重安1; 于明明2; 姜克俭1; 吴光华2. 亚须纤恙螨作为肾综合征出血热传播媒介初探[J]. 中国媒介生物学及控制杂志, 1998, 9(1): 47-50.
[2]	佘建军; 黄重安; 姜克俭. 陕西省姬鼠型出血热疫源地宿主动物和恙螨的调查研究[J]. 中国媒介生物学及控制杂志, 1995, 06(4): 286-290.