中国媒介生物学及控制杂志

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辽宁省肾综合征出血热Ⅰ、Ⅱ型灭活疫苗人体接种后抗体持续性观察

石英1; 赵铁镪1; 傅荣华1; 于泉福2; 杨国庆3; 李晓英3   

  1. 1辽宁省卫生防疫站; 2大洼县卫生防疫站; 3葫芦岛市卫生防疫站
  • 出版日期:1997-10-20 发布日期:1997-10-20

Continous Observation on the Level of Antibody after Iujection of Type Ⅰor Type Ⅱ Inactivated Vaccines against HFRS in Liaoning

Shi Ying*; Zhao Tie-qiang*; Fu Rong-hua; et al   

  1. *Liaoning Heralth and Anti-Epidemic Station,Shenyang 110005
  • Online:1997-10-20 Published:1997-10-20

摘要: 目的:观察HFRSⅠ、Ⅱ型灭活疫苗人体接种后的抗体持续性。方法:采用IFAT、MCPENT法检测荧光抗体及中和抗体。结果:大洼县用上海产沙鼠苗(Ⅰ型)加强免疫后回年,中和抗体阳性率为323%,荧光抗体阳性率为774%;葫芦岛市用地鼠苗(Ⅱ型)加强免疫后1年,中和抗体及荧光抗体阳性率分别为5.14%、77.1%。结论:两型疫苗免疫后抗体均有较好的保护性和持续性。

关键词: 肾综合征出血热, 灭活疫苗, 抗体

Abstract: The observation was carried out in Dawa and Huludao after the injection of Shanghai Mongoian gerbils kidney vaccines (Type Ⅰ) and hamster kidney vaccines (TyPe Ⅱ), respectively.1year after reinforced, the positive rates of neutralizing antithey were 32.3% in Dawa, 51.4% in Huludao, and the peitive rates of immunofluorescent antithey were 77.4% in Dawa, 77.1% in Huludao.