关键词: 杀虫剂, 家蝇, 飞翔肌线粒体, ATP酶

Abstract: This present paper dealt with the effects of organophosphates and pyreth roids on the mitoichondrial energy linked (Os-ligomycin-Sensitive Mg²⁺) ATPase from housefly flight muscles.The results showed that the ability of inhibition to OSMg-ATPase varied with the different structures of organophosphates and pyrethroids.Malathion, Phoxia and Acephate inhibited ATPase activity,but Fenthion was probably as an uncoupler and stimulate ATPase so that ATP hydrolysis was increased.The pyrethroids with the a-cyano group were much stronger to inhibit ATPase activity than the pyrethroids without the a-cyano group.The order of inhibition was as follows:Fenvalerate>Cypermethrin>Deltamethrin>Permethrin.The differences of organophosphates and pyrethroids to inhibit ATPase activity depended on temperatures.ATPase was more sensitive to Malathion and Phoxim at Ligher temperature,than at lower temperature,thus showing a positive temperature effect.In contrast.inhibition by permethrin and delamethrin showed a negative temperature effect.