关键词: 血清酸溶性蛋白, 疟原虫, 放线菌酮, 酮替芬, 氯喹, 青嵩素, 威灵仙

Abstract: This paper adopts the improved Bradford's Way to determine the content of serum ASP in mice infected with Plasmodium berghei and treated with actinone, chloroquine, ketotifeni, qinghaosu, weilingxian.The results reveal: the content of serum ASP in mice infecied with Plasrnodium berghei is heigher than that in normal mice markedly, it shows direct ratio relationship between the content and infective rate of Plasmodium; the content of serum ASP in mice treated with five antimalarial drugs lowers markedly, but there are differences between them, it displays inverse ratio relationship between the content and restrained rate of the drugs to plasmodium.The results show the determining content of serum ASP can be used as an index in Observing malarial course and determining effects of antimalarial drugs; it is also a better method in sieving antimalarial drugs.