Chines Journal of Vector Biology and Control ›› 2019, Vol. 30 ›› Issue (3): 248-251.DOI: 10.11853/j.issn.1003.8280.2019.03.004

• Scrub Typhus Special Report • Previous Articles     Next Articles

Seroepidemiological survey and risk factors analysis of scrub typhus in Changping district of Beijing, China

LI Sa1, WANG Rui-qin1, CAI Xu1, JIN Wen-jun1, LIU Zhong-cheng1, TANG Ya-qing1, TIAN Li-li2   

  1. 1 Changping District Center for Disease Control and Prevention, Beijing 102200, China;
    2 Beijing Center for Disease Control and Prevention
  • Received:2019-02-15 Online:2019-06-20 Published:2019-06-20


李飒1, 王瑞琴1, 蔡旭1, 金文军1, 刘重程1, 唐雅清1, 田丽丽2   

  1. 1 北京市昌平区疾病预防控制中心传染病与地方病控制科, 北京 102200;
    2 北京市疾病预防控制中心, 北京 100013
  • 通讯作者: 田丽丽,
  • 作者简介:李飒,女,硕士,医师,主要从事传染病预防与控制工作,


Objective To investigate the current infection status of scrub typhus and the risk factors for scrub typhus in Changping district of Beijing, China, and to provide a basis for the prevention and control strategies of scrub typhus. Methods The residents from 8 towns in Changping district were randomly selected to conduct a seroepidemiological survey from October to December, 2017. The risk factors for scrub typhus were analyzed. Independent chi-square test, stratified chi-square test, and trend chi-square test were used to analyze the infection rate between groups. Results A total of 480 serum samples were tested in this survey, of which 55 were positive for scrub typhus immunoglobulin G (IgG) antibody and the positive rate was 11.45%; there were significant differences in the positive rate between patients with different ages (χ2=57.712, P<0.001), education levels (χ2=35.257, P<0.001), and different occupations (χ2=17.222, P<0.001) and those in different regions (χ2=69.469, P<0.001). For farmers and serving officers, field work and walking or sitting on grass were risk factors for scrub typhus, respectively (odds ratio[OR]=3.03, 95% confidence interval[CI]:1.31-6.98; OR=3.18, 95%CI:1.07-9.46); spraying insect repellent and bathing or changing clothes after going out were protective factors, respectively (OR=0.45, 95%CI:0.21-0.98; OR=0.48, 95%CI:0.25-0.93). Conclusion The covert infection cases of scrub typhus are present in Changping district of Beijing, with significant population and regional differences, suggesting that it is necessary to strengthen surveillance, prevention, and control of scrub typhus and carry out further investigations.

Key words: Scrub typhus, Serological investigation, Infection rate, Risk factor


目的 调查昌平区恙虫病的感染现状及危险因素,为制定全区恙虫病的防控策略提供依据。方法 2017年10-12月,在昌平区8个镇随机抽取常住人口开展恙虫病血清流行病学调查并进行危险因素分析。分别采用独立χ2检验、分层χ2检验及趋势性χ2检验进行组间感染率分析。结果 本次调查共检测480份血清样本,其中55份恙虫病IgG抗体阳性,阳性率为11.45%;不同年龄(χ2=57.712,P<001)、教育程度(χ2=35.257,P<001)、职业(χ2=17.222,P<001)和地区(χ2=69.469,P<001)人群阳性率的差异有统计学意义。田间劳作(OR=3.03,95% CI:1.31~6.98)和草地行走(坐卧)(OR=3.18,95% CI:1.07~9.46)分别是农民和在职人员感染的危险因素。涂抹防虫剂(OR=0.45,95% CI:0.21~0.98)和外出后洗澡换衣(OR=0.48,95% CI:0.25~0.93)是保护因素。结论北京市昌平区存在恙虫病隐性感染病例且具有显著的人群和地区差异,提示应加强监测与防控并开展进一步的调查研究。

关键词: 恙虫病, 血清学调查, 感染率, 危险因素

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