Review

Research advances in key genes in prophenoloxidase-activating system of Musca domestica

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  • 1 School of Medicine and Life Science,University of Jinan, Jinan 250022, Shandong Province, China;
    2 Shandong Academy of Medical Sciences;
    3 Jinan Center for Disease Control and Prevention, Jinan 250021, Shandong Province, China

Received date: 2013-03-08

  Online published: 2013-08-20

Supported by

Supported by the Natural Science Foundation of Shandong Province(No. ZR2011CM012)and the Scientific and Technological Developing Project of Shandong Province(No. 2012GGB01172)

Abstract

Prophenoloxidase-activating system is an important part in the immune system of Musca domestica and plays an essential role in the pathogen recognition and immune defense. Until now, however, the key genes in the prophenoloxidase-activating system and the system's action mechanism remain unclear. On this occasion, we performed transcriptomic analysis of M. domestica to obtain a number of expressed sequence tags of the key genes of prophenoloxidases, prophenoloxidase-activating enzymes, serine proteinase inhibitors (Serpin), and upstream pattern-recognition receptors in the prophenoloxidase-activating system. This article reviews the research advances in the key genes in the prophenoloxidase-activating system of M. domestica.

Cite this article

LI Dian-xiang, ZHEN Tian-min, XIN Zheng, WANG Li-juan, MA Shu-fang, GUO Wen-zong, LIU Zheng-ming . Research advances in key genes in prophenoloxidase-activating system of Musca domestica[J]. Chinese Journal of Vector Biology and Control, 2013 , 24(4) : 367 -369 . DOI: 10.11853/j.issn.1003.4692.2013.04.029

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