Chines Journal of Vector Biology and Control ›› 2014, Vol. 25 ›› Issue (1): 72-75.DOI: 10.11853/j.issn.1003.4692.2014.01.021

• Investigation • Previous Articles     Next Articles

Laboratory and field evaluation on molluscicidal effect of quinoid-2′, 5-dichloro-4′-nitrosalicylanilide against Oncomelania hupensisfrom mountainous areas

ZHANG Jian-feng1, ZHU Ming-dong1, YAN Xiao-lan1, JIANG Neng-ming2, LIN Li-jun1,HUANG Li-lan2, YU Li-ling1, YE Xiao-dong2, WEN Li-yong1   

  1. 1 Institute of Parasitic Diseases Zhejiang Academy of Medical Sciences, Hangzhou 310013, Zhejiang Province, China;
    2 Jindong Center for Disease Control and Prevention
  • Received:2013-09-03 Online:2014-02-20 Published:2014-02-20
  • Contact: WEN Li-yong, Email: wenliyong@126.com

氯代水杨胺对山丘钉螺实验室和现场杀螺效果研究

张剑锋1,朱明东1,严晓岚1,蒋能明2,林丽君1,黄礼兰2,俞丽玲1,叶晓东2,闻礼永1   

  1. 1 浙江省医学科学院寄生虫病研究所,浙江 杭州 310013;
    2 金东区疾病预防控制中心
  • 通讯作者: 闻礼永, Email: wenliyong@126.com
  • 作者简介:张剑锋, 男, 硕士, 实验师, 主要从事血吸虫病流行病学和钉螺控制研究。Email: xszhangjianfeng@hotmail.com

Abstract: Objective To observe the molluscicidal effect of a novel molluscicide, 10% wettable powder of quinoid-2′,5-dichloro-4′-nitrosalicylanilide (LDS), on Oncomelania hupensis from the mountainous areas in Zhejiang province, China in the laboratory and field and to provide a scientific basis for the application of LDS in the field. Methods O. hupensis was immersed in 0.1, 0.2, 0.4, 0.6, or 0.8 mg/L LDS in the laboratory and field; 0.2, 0.4, 0.6, 0.8, or 1.0 g/m2 LDS was sprayed onto O. hupensis in the laboratory and field, or powder form of LDS was scattered onto O. hupensis in the field. Meanwhile, 50% wettable powder of niclosamide ethanolamine salt (WPN) and clean water were used as controls. The molluscicidal effects were evaluated. Results O. hupensis had mortality rates of 100% and over 95% after being immersed in 0.1 mg/L LDS for one day in the laboratory and field, respectively, with no significant differences compared without O. hupensis treated with WPN (P>0.05). O. hupensis had a mortality of over 95% after being sprayed with 0.8 g/m2 LDS for one day in the laboratory, a mortality of over 85% after being sprayed with 0.2 g/m2 LDS for three days in the field, and a mortality of over 85% after being scattered with 0.4 g/m2 LDS powder for one day in the field. The mortality of O. hupensis increased as the concentration of LDS rose and the exposure to LDS was prolonged. Conclusion LDS (10%) has a good molluscicidal effect on O. hupensis from mountainous areas of Zhejiang province in the laboratory and field.

Key words: Oncomelania hupensis, Quinoid-2′,5-dichloro-4′-nitrosalieylanilide, Molluscicidal effect, Mountainous area

摘要: 目的 观察新型灭螺药10%氯代水杨胺可湿性粉剂(LDS)对浙江省山丘地区钉螺和有螺环境的灭螺效果,为现场推广应用提供科学依据。方法 采用浓度0.1、0.2、0.4、0.6、0.8 mg/L的LDS分别进行实验室和现场浸杀法灭螺,采用浓度0.2、0.4、0.6、0.8、1.0 g/m2的LDS分别进行实验室喷洒法、现场喷洒法和撒粉法灭螺,同时设50%氯硝柳胺乙醇胺盐可湿性粉剂(WPN)药物对照和清水对照,观察药物的灭螺效果。结果 室内和现场浸杀试验LDS 0.1 mg/L浓度组,浸杀1 d钉螺死亡率分别达100%和95%以上,与WPN药物对照组相比差异无统计学意义(P>0.05);室内喷洒灭螺LDS 0.8 g/m2浓度组,喷洒1 d钉螺死亡率>95%,现场喷洒灭螺LDS 0.2 g/m2浓度组,喷洒3 d钉螺死亡率>85%,现场撒粉灭螺LDS 0.4 g/m2浓度组,撒粉后1 d钉螺死亡率>85%。各LDS试验组钉螺死亡率随着药物浓度的升高和作用时间的延长而升高。结论10% LDS对浙江省山丘地区钉螺和有螺环境具有较好的灭螺效果。

关键词: 钉螺, 氯代水杨胺, 杀螺效果, 山丘型

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