ISSN 1003-8280 CN 10-1522/R 中国疾病预防控制中心 主办
Chines Journal of Vector Biology and Control
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Lu Xiao-li; Zhao Tong-yuan; Xue Rui-de; Lu Bao-lin
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芦晓黎; 赵彤言; 薛瑞德; 陆宝麟
Abstract: In this paper,the C6/36 cell growth rate and karyokinesis, after adding the DM(10μg/ml、20μg/ml、40μg/ml) on culture, were dynamic observed using ictus method for revealing the effects of DM on C6/36 cell line proliferation.The inhibitory effects of higher DM on the cell line proliferation and a doseresponse effects were observed.The inhibited cells were regenerated after recession of DM treatment on the cell line.It was showed inhibitory effects of DM on the proliferation of C6/36 cell was reversible.
摘要: 目的:多侧面深入了解溴氰菊酯的毒性作用机制。方法:采用冲击式测试法(即药物与细胞接触时间有限,24小时),动态观察溴氰菊酯(浓度在40μg/ml以下)对C6/36细胞增殖的影响。结果:低浓度溴氰菊酯(10μg/ml)对C6/36细胞增殖没有影响,较高浓度溴氰菊酯(20μg/ml、40μg/ml)则对C6/36细胞增殖有明显抑制作用,抑制作用强度随药物浓度的增加而增加,去除药物作用后,受抑制的细胞又重新恢复生长、分裂。结论:这种抑制作用是可逆的。
关键词: 溴氰菊酯, 白纹伊蚊C6/36细胞株, 增殖, 抑制作用
Lu Xiao-li; Zhao Tong-yuan; Xue Rui-de; Lu Bao-lin. Inhibitory Effects of Deltamethrin(DM) on the Proliferation ofAedes albopictus C6/36 Cell Line and Regeneration of Inhibitied Cells[J]. Chines Journal of Vector Biology and Control.
芦晓黎; 赵彤言; 薛瑞德; 陆宝麟. 溴氰菊酯对白纹伊蚊C6/36细胞增殖的抑制作用及抑制后细胞的恢复[J]. 中国媒介生物学及控制杂志.
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