Objective A computer program was developed based on the internationally recognized statistics analysis system(SAS) to rapidly screen for the optimal synergistic formula for pesticide formulations. Methods Agents A and B were combined in a certain ratio and subject to the determination of toxicity against Tetranychus cinnabarinus and the computer program calculations for fitting the polynomial mathematical model of the co-toxicity coefficient (CTC), the arcsine transformation of the mass fraction. The derivative of the model curve was calculated and the maximum CTC and the optimal formulation ratio were computed. Results The polynomial mathematical model was statistically significant (F＝20.76, P＜0.05), the total coefficient of determination (R2)＝0.9540; the model equation was: CTC＝-2.021 499X2＋222.543 940X－5951.467 969; the derivation of the curve revealed the best extreme value X＝55.04, with the corresponding maximum CTC of 173.42 and the optimal formulation ratio of 2∶1. Conclusion Upon dual verification using program calculations, the established screening method proved to be an accurate, reliable, rapid and user-friendly approach to screen for the optimal synergistic formula.

　　【Abstract】　Objective　To explore a new kind of technique and method for the monitoring of pathogens carried by rats. Methods　According to the verification standard stipulated by sampler, use mathematic formula to count based on the statistics verification principle with the increase of surveillance samples. Draw the line of monitoring data on the graph. Distinguish quickly whether the carrying rate of pathogen exceeded the permission criteria or not, according to the relationship of monitoring line and up and down limitation.  Results　Take the surveillance of Hantaan virus (HV) carried by rats as example, the guard-line of virus carried by rat was assumed to  be 30%. The virus carrying rate of rats was periodically monitored by sequential sampling method. If the monitoring line was above the up limitation, suggesting that the level of HV carried by about 95% rats reached or exceeded 30%. Conclusion　The Sequential sampling method could make a relatively rapid and credible conclusion on the monitoring of pathogen carrier for its avoidance of blindness work and cost waste during the surveillance.

Objective To explore a new scientific method of medical-vector management, and grasp effectively the change of epidemic situation in time to provide a early warning. Methods The values of ,Rs,UWL,LWL,UCL,LCL were calculated by the method of quality control chart(QCC), and then X-R_s chart was drawn. Results According to the data in 2006, the analytical QCC was drawn to find that the interception rate of medical pest exceeded the UCL in June of 2006. After elimination abnormal points, it was found that the interception rate in April 2007 exceeded obviously standard value compared to that of January to May 2007 analyzed by the management QCC. It suggested that the CIQ Institution should enhance the inspection and quarantine to the disembarkation containers to prevent the introduction of vector. Conclusion The QCC can make precaution to epidemic situation captured from entry containers and help to CIQ Institution enhancing the inspection and quarantine to containers in the ports.